[健康人群在分级头高位倾斜过程中动脉顺应性和弹性的评估]

[Assessment of arterial compliance and elasticity during graded head-up tilt in healthy people].

作者信息

Guzik Przemysław, Bychowiec Bartosz, Gielerak Grzegorz, Greberski Krzysztof, Rzetecka Kinga, Wykretowicz Andrzej, Wysocki Henryk

机构信息

Katedra i Klinika Intensywnej Terapii Kardiologicznej i Chorób Wewnetrznych Akademii Medycznej w Poznaniu.

出版信息

Pol Merkur Lekarski. 2005 Jan;18(103):36-40.

PMID:15859544

Abstract

UNLABELLED

Head-up tilting causes many changes in cardiovascular system (CVS), and stimulates sympathetic nervous system, which leads to increase of total peripheral resistance (TPR) and acceleration of heart rate (HR). The hemodynamic changes influence pulse wave shape and mechanical properties of the arterial system. Arterial compliance (C) and elastance (Ea) are parameters used to describe mechanical properties of the arterial system. The study aim was to evaluate arterial stiffness by evaluation of arterial elastance and compliance during graded head-up tilting and assessment of the relationship between the change of the tilt angle and those parameters in healthy young subjects.

MATERIAL AND METHODS

The study was conducted in 32 healthy volunteers (21-30 years old, 17 female). After 20 minutes of supine rest, the head-up tilting was performed with the use of a tilt-table with electrical engine. The tilt-table was stopped for 1 minute after reaching the angle of 15 degrees and its multiples (i.e. 30, 45, 60, 75 and 90 degrees). Hemodynamic parameters were measured by means of chest bioelectrical impedance method (BioZcom monitor, CardioDynamics, USA). The association of the sine of the tilt angle with Ea and C was calculated with the use of Pearson correlation.

RESULTS

A strong positive correlation between the sine of the tilt angle and Ea was noted (r = 0. 5084; p < 0.0001). A negative correlation between the change of the tilt angle during head-up tilting and C was found (r = -0.4608; p < 0.0001).

CONCLUSION

During graded head-up tilting, arterial stiffness increases in young healthy people.

摘要

未标注

头高位倾斜会引起心血管系统（CVS）的许多变化，并刺激交感神经系统，导致总外周阻力（TPR）增加和心率（HR）加快。血流动力学变化会影响脉搏波形和动脉系统的力学特性。动脉顺应性（C）和弹性（Ea）是用于描述动脉系统力学特性的参数。本研究的目的是通过评估分级头高位倾斜过程中的动脉弹性和顺应性来评估动脉僵硬度，并评估健康年轻受试者倾斜角度变化与这些参数之间的关系。

材料与方法

本研究在32名健康志愿者（21 - 30岁，17名女性）中进行。仰卧休息20分钟后，使用电动倾斜台进行头高位倾斜。倾斜台在达到15度及其倍数角度（即3⃣0⃣、4⃣5⃣、6⃣0⃣🔟、7⃣5⃣和9⃣0⃣度）后停止1分钟。血流动力学参数通过胸部生物电阻抗法（BioZcom监测仪，美国CardioDynamics公司）测量。使用Pearson相关性计算倾斜角度的正弦值与Ea和C的关联。