Suppr超能文献

在伊利诺伊州,血管内动脉瘤修复对腹主动脉瘤治疗产生了多大程度的影响?

To what extent has endovascular aneurysm repair influenced abdominal aortic aneurysm management in the state of Illinois?

作者信息

Leon Luis R, Labropoulos Nicos, Laredo James, Rodríguez Heron E, Kalman Peter G

机构信息

Division of Vascular Surgery, Loyola University Medical Center, Stritch School of Medicine, Maywood, IL 60513, USA.

出版信息

J Vasc Surg. 2005 Apr;41(4):568-74. doi: 10.1016/j.jvs.2005.01.005.

Abstract

PURPOSE

This study was performed using population-based data to determine the changing trends in the techniques for abdominal aortic aneurysm (AAA) repair in the state of Illinois during the past 9 years and to examine the extent to which endovascular aneurysm repair (EVAR) has influenced overall AAA management.

METHODS

All records of patients who underwent AAA repair (1995 to 2003 inclusive) were retrieved from the Illinois Hospital Association COMPdata database. The outcome as determined by in-hospital mortality was analyzed according to intervention type (open vs EVAR) and indication (elective repair vs ruptured AAA). Data were stratified by age, gender, and hospital type (university vs community setting) and then analyzed using both univariate (chi 2 , t tests) and multivariate (stepwise logistic regression) techniques.

RESULTS

Between 1995 and 2003, 14,517 patients underwent AAA repair (85% for elective and 15% for ruptured AAA). The average age was 71.4 +/- 7.9 years, and 76% were men. For elective cases, open repair was performed in 86% and EVAR in 14%; and for ruptured cases, open repair in 97% and EVAR in 3%. Elective EVAR was associated with lower in-hospital mortality compared with open repair regardless of age. No differences were observed with age after either type of repair for a ruptured aneurysm. Men had a lower in-hospital mortality compared with women for open repair of both elective and ruptured aneurysms. For EVAR, the mortality of an elective repair was lower in men, but there was no difference after a ruptured AAA. In men, the difference in mortality between elective open repair and EVAR was significant; the type of institution did not influence outcome. Patients >80 years of age had a higher mortality after open repair for both elective and ruptured AAA and after EVAR of a ruptured AAA. The average length of stay was 9.9 days for open elective repair, 13.1 days after open repair of a ruptured AAA, and 3.6 days for EVAR. The independent predictors of higher in-hospital mortality were female gender, age >80 years, diagnosis (ruptured vs open), and procedure (open vs EVAR). The year of the procedure and type of hospital (university vs community) were not predictive of outcome.

CONCLUSIONS

EVAR has had a significant impact on AAA management in Illinois over a relatively short time period. In this population-based review, EVAR was associated with a significantly decreased in-hospital mortality and length of stay. Octogenarians had higher mortality after both types of repair, with the exception of elective EVAR.

摘要

目的

本研究利用基于人群的数据来确定过去9年伊利诺伊州腹主动脉瘤(AAA)修复技术的变化趋势,并探讨血管内动脉瘤修复术(EVAR)对整体AAA治疗的影响程度。

方法

从伊利诺伊州医院协会COMPdata数据库中检索所有接受AAA修复(包括1995年至2003年)患者的记录。根据干预类型(开放手术与EVAR)和适应症(择期修复与破裂性AAA)分析住院死亡率所确定的结果。数据按年龄、性别和医院类型(大学医院与社区医院)分层,然后使用单变量(卡方检验、t检验)和多变量(逐步逻辑回归)技术进行分析。

结果

1995年至2003年期间,14517例患者接受了AAA修复(85%为择期手术,15%为破裂性AAA)。平均年龄为71.4±7.9岁,76%为男性。对于择期病例,86%进行开放修复,14%进行EVAR;对于破裂病例,97%进行开放修复,3%进行EVAR。无论年龄如何,择期EVAR与开放修复相比住院死亡率较低。对于破裂性动脉瘤,两种修复方式后的死亡率在年龄方面均未观察到差异。对于择期和破裂性动脉瘤的开放修复,男性的住院死亡率低于女性。对于EVAR,择期修复男性的死亡率较低,但破裂性AAA后无差异。在男性中,择期开放修复与EVAR之间的死亡率差异显著;机构类型不影响结果。80岁以上患者在择期和破裂性AAA开放修复后以及破裂性AAA的EVAR后死亡率较高。择期开放修复的平均住院时间为9.9天,破裂性AAA开放修复后为13.1天,EVAR为3.6天。住院死亡率较高的独立预测因素为女性、年龄>80岁、诊断(破裂与开放)和手术方式(开放与EVAR)。手术年份和医院类型(大学医院与社区医院)不能预测结果。

结论

在相对较短的时间内,EVAR对伊利诺伊州的AAA治疗产生了重大影响。在这项基于人群的综述中,EVAR与显著降低的住院死亡率和住院时间相关。除择期EVAR外,80岁以上患者在两种修复方式后的死亡率均较高。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验