屈指肌腱手术的未来。

The future of flexor tendon surgery.

作者信息

Luo Jeffrey, Mass Daniel P, Phillips Craig S, He T C

机构信息

Department of Surgery, University of Chicago Hospitals, 5841 South Maryland Avenue, MC 3079, Chicago, IL 60637, USA.

出版信息

Hand Clin. 2005 May;21(2):267-73. doi: 10.1016/j.hcl.2005.01.001.

DOI:10.1016/j.hcl.2005.01.001

PMID:15882605

Abstract

Clinical outcomes following flexor tendon repair have made significant improvements in the last 50 years. In that time standard treatment has evolved from secondary grafting to primary repair with postoperative rehabilitation protocols. Unfortunately, excellent results are not yet attained universally following treatment. Improving understanding of tendon healing at the cellular, molecular, and genetic levels will likely enable surgeons to modulate the normal repair process. We now look toward biologic augmentation of flexor tendon repairs to address the problems of increasing tensile strength while reducing adhesion formation following injury and operative repair.

摘要

在过去50年里，屈指肌腱修复后的临床疗效有了显著改善。在此期间，标准治疗方法已从二期移植发展为一期修复并辅以术后康复方案。不幸的是，治疗后并非总能普遍获得优异的效果。增进对肌腱在细胞、分子和基因水平愈合过程的理解，可能会使外科医生能够调控正常的修复过程。我们现在期待通过生物增强技术来改进屈指肌腱修复，以解决在损伤和手术修复后提高拉伸强度同时减少粘连形成的问题。