Gross A J, Busse M, Leonard J, Schumacher H
Marien Krankenhaus, Bergisch-Gladbach, Germany.
Prostate Cancer Prostatic Dis. 2005;8(3):210-4. doi: 10.1038/sj.pcan.4500803.
The aim of this observational prospective study was to evaluate the switch from phytotherapy to tamsulosin 0.4 mg once daily (o.d.) on efficacy, sexual function and tolerability in patients with lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH) who have a poor response to at least 4 weeks of phytotherapy. The switch to tamsulosin 0.4 mg o.d. improves LUTS and related quality of life. Sexual function is also slightly improved. Tamsulosin is as well tolerated as phytotherapy and abnormal ejaculation appears to be no problem. Tamsulosin is perceived by both patients and urologists to be superior to preceding phytotherapy.
这项观察性前瞻性研究的目的是评估在接受至少4周植物疗法后反应不佳的下尿路症状/良性前列腺增生(LUTS/BPH)患者中,从植物疗法转换为每日一次服用0.4毫克坦索罗辛的疗效、性功能和耐受性。转换为每日一次服用0.4毫克坦索罗辛可改善LUTS及相关生活质量。性功能也略有改善。坦索罗辛的耐受性与植物疗法相当,异常射精似乎不是问题。患者和泌尿科医生都认为坦索罗辛优于之前的植物疗法。