Flores-Alvarado Luis Javier, Sánchez-Enríquez Sergio, Moreno Abraham Zepeda, Ramírez-Garcial Sergio Alberto, Bueno-Topete Miriam Ruth, Ayub-Ayala Mónica, del Vázquez-López Lucía Sagrario, Gallardo-Meza Antonio, Nuño-Moren Patricia, Gaspar-Barba César Enrique
Laboratorio de Bioquímica, Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara.
Gac Med Mex. 2005 Mar-Apr;141(2):157-60.
A 19 moth-old child who presented seizures secondary to intractable hypoglycemia, fulfilling the clinical and biochemical criteria for hyperinsulinism was studied. Histopathological findings of the pancreas showed the presence of small clusters of b cell islets throughout acinar tissue near ducts, in both the head and the proximal third of the body. Proximal pancreatectomy (60%) and distal pancreatic-jejunostomy (Roux-in-Y) were performed. This procedure was effective in reverting hypoglycemia and constitutes the first successful alternative treatment.
一名19个月大的儿童因顽固性低血糖继发癫痫发作,符合高胰岛素血症的临床和生化标准,对其进行了研究。胰腺的组织病理学检查结果显示,在胰头和胰体近端三分之一处靠近导管的腺泡组织中均存在小簇的β细胞胰岛。实施了近端胰腺切除术(60%)和远端胰空肠吻合术(Roux-en-Y)。该手术有效逆转了低血糖,是首个成功的替代治疗方法。