Sema Kaori, Takei Masami, Uenogawa Kumi, Horikoshi Akira, Hosokawa Yoshifumi, Matsuda Masakazu, Henmi Akihiro, Sawada Shigemasa
Department of Internal Medicine, Nerima Hikarigaoka Nihon University Hospital, Tokyo.
Intern Med. 2005 Apr;44(4):335-41. doi: 10.2169/internalmedicine.44.335.
A 68-year-old woman with Felty's syndrome was admitted to our hospital due to breathlessness. She was diagnosed as having rheumatoid arthritis at age 59 years. Abdominal computed tomography indicated ascites, splenomegaly and liver atrophy. She had no antigens or antibodies for hepatitis virus, or antibodies for mitochondria with the exception of antinuclear antibody. According to the International Autoimmune Hepatitis (AIH) scoring system, she was diagnosed as having chronic hepatitis, compatible with AIH. The association of Felty's syndrome with AIH is very rare and the most difficult problem to overcome is whether or not steroid therapy is necessary in patients with Felty's syndrome complicated by AIH.
一名68岁患有费尔蒂综合征的女性因呼吸困难入住我院。她在59岁时被诊断为类风湿关节炎。腹部计算机断层扫描显示有腹水、脾肿大和肝萎缩。除抗核抗体外,她没有针对肝炎病毒的抗原或抗体,也没有线粒体抗体。根据国际自身免疫性肝炎(AIH)评分系统,她被诊断为患有慢性肝炎,符合AIH。费尔蒂综合征与AIH的关联非常罕见,最难以解决的问题是费尔蒂综合征合并AIH的患者是否需要进行类固醇治疗。