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大鼠部分胼胝体切开术与左右反应分化:前后促进作用的分离

Partial callosotomy and left-right response differentiation in the rat: separate anterior and posterior facilitatory effects.

作者信息

Noonan M, Axelrod S

机构信息

Department of Psychology, Canisius College, Buffalo, New York 14208.

出版信息

Behav Neurosci. 1992 Apr;106(2):433-6. doi: 10.1037//0735-7044.106.2.433.

DOI:10.1037//0735-7044.106.2.433
PMID:1590961
Abstract

Earlier research demonstrated that complete section of the corpus callosum in the rat reduced the number of trials required to acquire a left-right response differentiation (LRRD). This study was designed to investigate whether the facilitatory effect on LRRD could be produced by section of an anatomical subdivision of the callosum. Rats with sections of the anterior or posterior corpus callosum mastered the LRRD task faster than sham subjects, but more slowly than rats with total callosal section; section of the middle portion of the callosum had no such effect. The partial facilitatory effects of anterior and posterior callosotomy appear to be independent, and suggest that the callosal intermixing of lateral information, which contributes to left-right confusion, occurs at both the sensory and motor levels of processing.

摘要

早期研究表明,切断大鼠的胼胝体可减少获得左右反应分化(LRRD)所需的试验次数。本研究旨在调查胼胝体的一个解剖亚区的切断是否能产生对LRRD的促进作用。切断胼胝体前部或后部的大鼠比假手术组更快地掌握了LRRD任务,但比完全切断胼胝体的大鼠慢;切断胼胝体中部则没有这种效果。胼胝体前部和后部切开的部分促进作用似乎是独立的,这表明导致左右混淆的侧向信息在胼胝体中的混合发生在感觉和运动处理水平。

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