de la Peña-Almaguer Erasmo, Azpiri López José Ramón, González-Camid Felipe de Jesús, Ponce de León Enrique, Flores-Ramírez Ramiro, Zamarripa Rafael, Loera Javier, Rodríguez Daniel, González Quijano Rafael, Azpiri-Magallanes Marcela, Jaramillo Estrada Samuel, Assad Morell José Luis
Departamento de Imagenología Cardiovascular, Hospital Christus-Muguerza de Monterrey, Hidalgo 2525 Pte, col. Obispado, Monterrey, NL 64040.
Arch Cardiol Mex. 2005 Jan-Mar;75(1):55-60.
The evaluation of Left ventricular function has both prognostic as well as therapeutic implications in patients with heart disease. Non-invasive coronary angiography with computed tomography using 16 slices (MDCT-16) allows to obtain images of the coronary anatomy due to its high spatial and temporal resolution, and also, to obtain data regarding Left ventricular function. The objective of this study was to correlate the use of MDCT-16 for the evaluation of the Left ventricular parameters using MRI as the Standard of reference.
MRI: Se A 1.5 Tesla GE CvI Scanner optimized for cardiovascular applications was used. Using an ECG gated steady state fast precession sequence (SSFP, Thickness 10 mm, Flip Angle 45, FOV 36 cm. NEX 1, Frequency 256, Phase 128, Partial FOV 0.75, 16VPS), 6 to 8 short axis images of from base to apex of the left ventricle were obtained. Tomography: Using a 16 slice Multidetector tomograph (GE Lightspeed) and using ECG synchronization, images of the heart were obtained after the administration of 80 mls. of no-ionic contrast. The images were reconstructed off-line to obtain from 6 to 8 slices in a similar fashion to that of MR. Both studies were independently analyzed by 2 operators who obtained the ventricular function data. Linear correlation and a Paired T Student test was used to analyze the data and was considered significant when p < 0.05.
20 consecutive patients were evaluated with MDCT-16 and MRI, 18 males, mean age 52 +/- 15 years. There was no significant difference among the measurements for cardiac CT and MRI of the end-diastolic volume (EDV) and end-sistolic volume (ESV), stroke volume (SV), LV Mass or LV ejection fraction (LVEF).
This results show a high correlation among the clinically relevant ventricular function parameters evaluated by cardiovascular CT and MRI. This findings suggest that ventricular function can be successfully evaluated along with the coronary anatomy using MDCT-16.
对心脏病患者左心室功能的评估具有预后及治疗意义。使用16层螺旋CT（MDCT - 16）进行无创冠状动脉造影，因其具有高空间和时间分辨率，能够获取冠状动脉解剖图像，同时也能获取有关左心室功能的数据。本研究的目的是将MDCT - 16用于评估左心室参数的结果与以MRI作为参考标准的结果进行对比。
MRI：使用一台为心血管应用优化的1.5特斯拉GE CvI扫描仪。采用心电图门控稳态快速进动序列（SSFP，层厚10毫米，翻转角45°，视野36厘米，激励次数1，频率256，相位128，部分视野0.75，16层/秒），获取6至8个从左心室基部到心尖的短轴图像。断层扫描：使用16层多探测器断层扫描仪（GE光速）并采用心电图同步，在静脉注射80毫升非离子型造影剂后获取心脏图像。图像离线重建，以类似于MRI的方式获取6至8层图像。两项研究均由两名获取心室功能数据的操作人员独立分析。采用线性相关分析和配对t检验分析数据，当p < 0.05时认为差异具有统计学意义。
连续20例患者接受了MDCT - 16和MRI检查，其中男性18例，平均年龄52±15岁。心脏CT和MRI测量的舒张末期容积（EDV）、收缩末期容积（ESV）、每搏输出量（SV）、左心室质量或左心室射血分数（LVEF）之间无显著差异。
这些结果表明，心血管CT和MRI评估的临床相关心室功能参数之间具有高度相关性。这些发现提示，使用MDCT - 16可以在评估冠状动脉解剖结构的同时成功评估心室功能。
