Shiraishi Shuichi, Uemura Hideki, Kagisaki Koji, Koh Masahiro, Yagihara Toshikatsu, Kitamura Soichiro
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan.
Ann Thorac Surg. 2005 Jun;79(6):2083-7; discussion 2087-8. doi: 10.1016/j.athoracsur.2004.11.056.
We previously used the Fontan procedure, when applicable, by placing a temporary bypass from the inferior vena cava to the atrium. Alternatively, we have striven to achieve the procedure even without use of a temporary bypass in patients having collaterals between the inferior vena cava and the superior vena cava, so as to simplify the procedure. The azygous vein was intentionally left patent at the bidirectional Glenn procedure in the most recent 9 patients, expecting reasonable venovenous communication at Fontan completion. Surgical results will be described for the preliminary experience.
Since 2001, this alternative technique has been attempted in 34 patients undergoing the staged Fontan procedure, and eventually used in 22. Duration between the staged procedures was 4 to 108 months (median, 10 months). We considered that the technique was feasible unless femoral venous pressure exceeded 20 mm Hg immediately after cross-clamping the inferior vena cava. Although catheterization before the Fontan completion illustrated development of venovenous collaterals in 14 patients, oxygen saturation remained greater than 80% throughout the period of the bidirectional Glenn physiology.
In all 22 patients, the extracardiac channel was readily reconstructed with an excellent surgical field of view, without operative mortality. On cross-clamping the inferior vena cava, the systemic circulation could be well maintained by administration of dopamine. Oxygen saturation immediately became approximately 97% to 100%. Maximal pressure gradient was 11 +/- 5 mm Hg between the superior vena cava and the femoral vein. Postoperatively, serum concentration of enzymes did not critically increase (maximal aspartate transaminase, 96 +/- 89 U/L; alanine transaminase, 65 +/- 59 U/L; total bilirubin, 1.8 +/- 1.1 mg/dL; creatine kinase, 437 +/- 230 U/L).
This alternative technique, when feasible under the current criteria, was simple and did not provide any clinically significant impediments.
我们之前在适用时采用Fontan手术,即从下腔静脉到心房建立临时旁路。另外,对于下腔静脉和上腔静脉之间存在侧支循环的患者,我们努力在不使用临时旁路的情况下完成该手术,以简化手术过程。在最近的9例患者的双向格林手术中,故意保留奇静脉通畅,期望在Fontan手术完成时实现合理的静脉-静脉分流。将描述初步经验的手术结果。
自2001年以来,这种替代技术已在34例接受分期Fontan手术的患者中尝试,最终在22例患者中使用。分期手术之间的间隔为4至108个月(中位数为10个月)。我们认为,当下腔静脉交叉钳夹后股静脉压力不超过20 mmHg时,该技术是可行的。尽管在Fontan手术完成前的导管检查显示14例患者存在静脉-静脉侧支循环形成,但在双向格林生理阶段,氧饱和度始终保持在80%以上。
在所有22例患者中,心外通道均易于重建,手术视野良好,无手术死亡。在下腔静脉交叉钳夹时,通过给予多巴胺可良好维持体循环。氧饱和度立即升至约97%至100%。上腔静脉与股静脉之间的最大压力梯度为11±5 mmHg。术后,酶的血清浓度未显著升高(最高谷草转氨酶为96±89 U/L;谷丙转氨酶为65±59 U/L;总胆红素为1.8±1.1 mg/dL;肌酸激酶为437±230 U/L)。
在当前标准下可行时,这种替代技术简单,且未造成任何临床上的重大阻碍。