[人体营养中的铜：吸收与生物利用度]

[Copper in nutrition man: absorption and bioavailability].

作者信息

Mazo V K, Shirina L I

出版信息

Vopr Pitan. 2005;74(2):52-9.

Abstract

The bioavailability of copper is characterized by the efficiency of gastrointestinal absorption of this microelement and its further utilization. The paths of intestinal absorption of copper, further carrier in the blood and in hepatocites are investigated in the experiences on animals and on healthy volunteers with the use of stable isotopes 65Cu and 63Cu. Enterohepatic circulation and bile secretion control the maintenance of copper nutritional status besides the intestinal absorption of copper. The role of a series of the food factors in absorption of copper in gastrointestinal tract is considered, major of which being proteins, amino acides, fructose, ascorbic acid, phytates, divalent cations and some other components of food.

摘要

铜的生物利用度取决于该微量元素在胃肠道的吸收效率及其进一步的利用情况。利用稳定同位素⁶⁵Cu和⁶³Cu，在动物实验和健康志愿者实验中研究了铜在肠道的吸收途径、在血液和肝细胞中的进一步载体。除了肠道对铜的吸收外，肠肝循环和胆汁分泌也控制着铜营养状况的维持。研究了一系列食物因素在胃肠道铜吸收中的作用，其中主要的有蛋白质、氨基酸、果糖、抗坏血酸、植酸盐、二价阳离子和食物中的其他一些成分。