Aydin Erdinc, Turkoglu Seda, Ozen Ozlem, Akkuzu Babur
Baskent University Faculty of Medicine, Department of Otorhinolaryngology & Head and Neck Surgery 6. Cadde No. 72/2, 06490 Bahcelievler, Ankara, Turkey.
Auris Nasus Larynx. 2005 Sep;32(3):301-4. doi: 10.1016/j.anl.2005.03.018.
Mucinous cystadenocarcinoma of the salivary gland is a rare entity that has only recently been described. This lesion was included in the 1991 World Health Organization Classification as "papillary cystadenocarcinoma," and that same year the United States Armed Forces Institute of Pathology classified it as "cystadenocarcinoma with or without a papillary component." Only a small proportion of salivary gland tumors are adenocarcinomas. Most mucinous cystadenocarcinomas affect the major salivary glands, particularly the parotid. These are low-grade malignancies, and most that occur in the minor salivary glands show very little aggressive behavior. These tumors are histologically similar to adenocarcinomas of the gastrointestinal tract. It is often difficult to differentiate them from other neoplasms. The differential diagnosis includes mucoepidermoid carcinoma, acinic cell carcinoma, salivary duct carcinoma, nasal adenocarcinoma, and metastatic carcinoma. This report describes the case of an 80-year-old man who presented with a painless swelling in his right upper lip that had been present for 1 month. Fine-needle aspiration biopsy of the lesion revealed inflammatory cells without an epithelial component. The treatment was wide excision, and there was no recurrence during 6 months of follow-up. The pathological diagnosis was low-grade mucinous cystadenocarcinoma of a minor salivary gland.
涎腺黏液性囊腺癌是一种罕见的疾病，直到最近才被描述。该病变在1991年世界卫生组织分类中被列为“乳头状囊腺癌”，同年美国武装部队病理研究所将其分类为“有或无乳头状成分的囊腺癌”。涎腺肿瘤中只有一小部分是腺癌。大多数黏液性囊腺癌累及大涎腺，尤其是腮腺。这些是低级别恶性肿瘤，大多数发生在小涎腺的肿瘤侵袭性很小。这些肿瘤在组织学上与胃肠道腺癌相似。通常很难将它们与其他肿瘤区分开来。鉴别诊断包括黏液表皮样癌、腺泡细胞癌、涎腺导管癌、鼻腺癌和转移癌。本报告描述了一名80岁男性的病例，他的右上唇出现无痛性肿胀1个月。对该病变进行细针穿刺活检，结果显示为炎症细胞，无上皮成分。治疗方法是广泛切除，随访6个月期间无复发。病理诊断为小涎腺低级别黏液性囊腺癌。
