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一项关于1958年出生队列父母健康与死亡风险的代际及生命历程研究:(I)方法与追踪

An intergenerational and lifecourse study of health and mortality risk in parents of the 1958 birth cohort: (I) methods and tracing.

作者信息

Hyppönen Elina, Davey Smith George, Shepherd Peter, Power Chris

机构信息

Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health,30 Guilford Street, London WC1N 1EH, UK.

出版信息

Public Health. 2005 Jul;119(7):599-607. doi: 10.1016/j.puhe.2004.11.003.

Abstract

OBJECTIVES

This paper describes the methods used to obtain information on mortality and cancer registrations for the parents of the British 1958 birth cohort, in order to create a dataset that can be used to examine intergenerational relationships on health and growth.

STUDY DESIGN

Intergenerational cohort study.

METHODS

The 1958 cohort includes all births occurring during 1 week in March 1958 in England, Scotland and Wales. For more than four decades of follow-up, information has been collected on cohort members, their parents and children. Information on the National Health Service (NHS) numbers of the parents was not available, but other details were collated for the Office for National Statistics to trace and flag the biological parents of the cohort members.

RESULTS

Tracing was successful in 90.2% of fathers (n = 14,334) and 94.9% of mothers (n = 15,076). The greatest success was achieved for parents in families where there was no indication for additional mother or father figures until the child was 16 years old (96.6% of the mothers traced, n = 14,274; 94.3% of the fathers traced, n = 13,256). Tracing rates were lower than average in unmarried mothers (59%) and for the small group who were separated, widowed or divorced in 1958 (81%); the rates were particularly poor for the corresponding fathers (24.4 and 54.7%, respectively). There were only small variations in tracing rates between different regions of Britain.

CONCLUSIONS

The tracing rates achieved were generally very high despite the lack of NHS number, especially where there was family stability throughout the childhood of cohort members. Parental status will need to be considered in future studies. With the high tracing rates achieved, the dataset provides an important resource with which to evaluate multigenerational associations with health and development in parents, their offspring and grandchildren.

摘要

目的

本文描述了用于获取英国1958年出生队列父母的死亡率和癌症登记信息的方法,以便创建一个可用于研究健康与成长方面代际关系的数据集。

研究设计

代际队列研究。

方法

1958年队列包括1958年3月在英格兰、苏格兰和威尔士某一周内出生的所有婴儿。在四十多年的随访中,收集了队列成员、他们的父母和子女的信息。父母的国民健康服务(NHS)号码信息无法获取,但为国家统计局整理了其他详细信息,以追踪并标记队列成员的亲生父母。

结果

90.2%的父亲(n = 14,334)和94.9%的母亲(n = 15,076)追踪成功。对于孩子16岁之前没有额外母亲或父亲角色迹象的家庭中的父母,追踪成功率最高(96.6%的母亲被追踪到,n = 14,274;94.3%的父亲被追踪到,n = 13,256)。未婚母亲的追踪率低于平均水平(59%),以及1958年分居、丧偶或离婚的小群体的追踪率也较低(81%);相应父亲的追踪率尤其低(分别为24.4%和54.7%)。英国不同地区之间的追踪率只有微小差异。

结论

尽管没有NHS号码,但追踪率总体上非常高,特别是在队列成员整个童年时期家庭稳定的情况下。未来的研究需要考虑父母的状况。鉴于实现了高追踪率,该数据集为评估父母、其子女和孙辈在健康与发育方面的多代关联提供了重要资源。

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