Park D J, Lee H-J, Kim H-H, Yang H-K, Lee K U, Choe K J
Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Br J Surg. 2005 Sep;92(9):1099-102. doi: 10.1002/bjs.4952.
The aim of this study was to identify factors that predict morbidity and mortality in gastric cancer surgery.
Data on 719 consecutive patients who underwent operations for gastric cancer at Seoul National University Hospital between January and December 2002 were reviewed.
Overall morbidity and mortality rates were 17.4 per cent (125 patients) and 0.6 per cent (four patients) respectively, and the rates of surgical and non-surgical complications were 14.7 per cent (106 patients) and 3.3 per cent (24 patients). Morbidity rates were higher in patients aged over 50 years (odds ratio (OR) 1.04 (95 per cent confidence interval (c.i.) 1.02 to 1.06)), when the gastric tumour was resected with another organ (36 per cent for combined resection versus 15.4 per cent for gastrectomy only; OR 3.25 (95 per cent c.i. 1.76 to 6.03)) and when gastrojejunostomy was used for reconstruction after subtotal gastrectomy (17.0 per cent for Billroth II versus 9.5 per cent for Billroth I; OR 2.00 (95 per cent c.i. 1.05 to 3.79)). Only three patients (2.8 per cent) with a surgical complication underwent reoperation, two for adhesive obstruction and one for intra-abdominal bleeding.
Age, combined resection and Billroth II reconstruction after radical subtotal gastrectomy were independently associated with the development of complications after gastric cancer surgery.
本研究旨在确定预测胃癌手术发病率和死亡率的因素。
回顾了2002年1月至12月在首尔国立大学医院连续接受胃癌手术的719例患者的数据。
总体发病率和死亡率分别为17.4%(125例患者)和0.6%(4例患者),手术并发症和非手术并发症的发生率分别为14.7%(106例患者)和3.3%(24例患者)。50岁以上患者的发病率较高(优势比(OR)为1.04(95%置信区间(c.i.)为1.02至1.06)),当胃肿瘤与另一器官一起切除时(联合切除为36%,单纯胃切除为15.4%;OR为3.25(95% c.i.为1.76至6.03)),以及当胃大部切除术后采用胃空肠吻合术进行重建时(毕Ⅱ式为17.0%,毕Ⅰ式为9.5%;OR为2.00(95% c.i.为1.05至3.79))。只有3例(2.8%)手术并发症患者接受了再次手术,2例因粘连性肠梗阻,1例因腹腔内出血。
年龄、联合切除以及根治性胃大部切除术后的毕Ⅱ式重建与胃癌手术后并发症的发生独立相关。