由3-乙氧基α,β-不饱和内酯一步合成2,3-二氢-4H-吡喃-4-酮。
A one-step synthesis of 2,3-dihydro-4H-pyran-4-ones from 3-ethoxy alpha,beta-unsaturated lactones.
作者信息
Winkler Jeffrey D, Oh Kyungsoo
机构信息
Department of Chemistry, The University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
出版信息
Org Lett. 2005 Jun 9;7(12):2421-3. doi: 10.1021/ol050702z.
PMID:15932213
Abstract
[reaction: see text] Addition of diverse nucleophiles to the unsaturated lactone 2 that results from hetero Diels-Alder reaction of Brassard's diene 1 with aldehydes leads to an efficient and general approach to the synthesis of 2,3-dihydro-4H-pyran-4-ones 3.
摘要
[反应：见正文] 将多种亲核试剂添加到由布拉萨德二烯1与醛进行杂环狄尔斯-阿尔德反应生成的不饱和内酯2中，可提供一种高效且通用的方法来合成2,3-二氢-4H-吡喃-4-酮3。
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