Jayasinghe Yasmin, Rane Ajay, Stalewski Harry, Grover Sonia
Department of Paediatric and Adolescent Gynaecology, Royal Children's Hospital, Melbourne, Australia.
Obstet Gynecol. 2005 Jun;105(6):1456-67. doi: 10.1097/01.AOG.0000161321.94364.56.
The key to successful management of the rudimentary uterine horn is early detection. This review of the literature seeks to illustrate important aspects of diagnosis and management of this anomaly.
An English language MEDLINE search from 1966 to 2003 was performed, using the search terms "rudimentary uterine horn," "accessory horn," "uterus bicornis unicollis," "hematometra," "unicornuate or bicornuate uterus," and "mullerian anomaly." References from previously published sources were also obtained.
One hundred thirty letters, case reports, case series, and review articles featuring rudimentary uterine horn were found. Reports before 1966 were excluded because outcomes before the advent of modern diagnostic techniques were not relevant to this study.
TABULATION, INTEGRATION, AND RESULTS: Three hundred sixty-six rudimentary horn presentations (210 gynecologic and 156 obstetric) were found. Noncommunicating horns accounted for 92% of cases (95% confidence interval [CI] 88-95%, P < .001), and renal anomaly was found in 36% (95% CI 29-44%). Contrary to the American Fertility Society classification of uterine anomalies, rudimentary horns may occur without a corresponding unicornuate uterus. The mean age of presentation was similar for gynecologic and obstetric presentations (23 and 26 years, 95% CIs 21.2-24.6 and 124.9-27.3 years, respectively). Presentation in the third decade of life or later occurred in 78% of patients (95% CI 70-84%, P < .001). Sensitivity of ultrasound examination for diagnosis was 26% (95% CI 18-36%). Diagnosis before clinical symptoms occurred in 14% (95% CI 7-23%).
Many functional noncommunicating horns present during or after the third decade of life with acute obstetric uterine rupture. Surgical removal before pregnancy is recommended. Rates of prerupture diagnosis remain disappointingly low.
成功管理残角子宫的关键在于早期发现。本文献综述旨在阐述这种异常情况诊断和管理的重要方面。
利用检索词“残角子宫”“副角”“双角单颈子宫”“子宫积血”“单角或双角子宫”以及“苗勒管异常”,对1966年至2003年的英文医学文献数据库进行检索。还获取了先前已发表文献的参考文献。
共找到130篇涉及残角子宫的信函、病例报告、病例系列及综述文章。1966年以前的报告被排除,因为现代诊断技术出现之前的结果与本研究无关。
制表、整合及结果:共发现366例残角子宫病例(210例妇科病例和156例产科病例)。非交通性残角子宫占病例的92%(95%置信区间[CI]88 - 95%,P <.001),36%(95%CI 29 - 44%)的病例存在肾脏异常。与美国生育协会对子宫异常的分类相反,残角子宫可能在没有相应单角子宫的情况下出现。妇科和产科病例的平均就诊年龄相似(分别为23岁和26岁,95%CI分别为21.2 - 24.6岁和24.9 - 27.3岁)。78%的患者在30岁及以后出现症状(95%CI 70 - 84%,P <.001)。超声检查诊断的敏感性为26%(95%CI 18 - 36%)。14%(95%CI 7 - 23%)的病例在出现临床症状之前得到诊断。
许多功能性非交通性残角子宫在30岁及以后出现,伴有急性产科子宫破裂。建议在怀孕前进行手术切除。破裂前的诊断率仍然低得令人失望。