Fumal I, Piérard-Franchimont C, Piérard G E
CHR hutois, Service de Dermatologie, Huy.
Rev Med Liege. 2005 Apr;60(4):217-21.
We report the case of a 70-year old man who presented the classical cutaneous signs of chronic arsenicism : palmo-plantar keratoses and lesions of Bowen's disease. Within a few months, the patient developed multiple large superficial basal cell carcinomas on the trunk and several invasive squamous cell carcinomas. A pulmonary cancer with cerebral metastases was also identified. The complications of chronic arsenicism are nowadays rarely encountered. The cutaneous changes should be recongized because they allow to reveal the etiology of some internal lesions. Indeed, the notion of past arsenicism is often missing in the patient records. The recognition of the cutaneous warning signs allows to focus on the overall cancer risk of these patients.
我们报告了一例70岁男性患者的病例,该患者出现了慢性砷中毒的典型皮肤症状:掌跖角化病和鲍恩病病变。在几个月内,患者躯干上出现了多个大型浅表基底细胞癌以及数例浸润性鳞状细胞癌。还发现了伴有脑转移的肺癌。如今,慢性砷中毒的并发症很少见。应认识到皮肤变化,因为它们有助于揭示一些内部病变的病因。实际上,患者记录中常常缺少既往砷中毒的信息。识别皮肤警示信号有助于关注这些患者的整体癌症风险。