Kim Myungshin, Lim Jihyang, Kim Yonggoo, Han Kyungja, Lee Seok, Min Chang Kee
Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, 62 Youido-dong, Youngdeungpo-gu, St Mary's Hospital, Seoul, 150-713, Korea.
Ann Clin Lab Sci. 2005 Spring;35(2):195-8.
We describe an unusual case of acute promyelocytic leukemia with +der(17)t(15;17) as the additional cytogenetic abnormality and with t(15;17) defined by fluorescence in situ hybridization (FISH) using a PML/RARA dual color, dual fusion translocation probe. By performing a step-by-step, complementary approach to evaluate unusual chromosomal abnormalities, we detected RARA/PML fusion on a marker chromosome similar to chromosome 17.
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