Montgomery Catharine, Fisk John E, Newcombe Russell, Wareing Michelle, Murphy Philip N
School of Psychology, Liverpool John Moores University, UK.
Exp Clin Psychopharmacol. 2005 May;13(2):137-45. doi: 10.1037/1064-1297.13.2.137.
Previous research has demonstrated working memory and executive deficits in recreational users of MDMA (3,4-methylenedioxymethamphetamine; Ecstasy). In turn, both of these constructs have been implicated in syllogistic reasoning performance. Twenty-two MDMA users (mean age = 21.36) and 26 MDMA nonuser controls (mean age = 21.31) were tested on syllogisms of varying difficulty and on measures of working memory and executive functioning. MDMA users were significantly impaired in aspects of syllogistic reasoning, and the effect remained significant after the authors controlled for the use of other drugs. However, the MDMA-related variance was reduced to below statistical significance following control for group differences in working memory span. The results are consistent with the possibility that MDMA-related deficits in aspects of executive functioning result in impaired reasoning performance among MDMA users.
先前的研究已证明，摇头丸（3,4－亚甲基二氧甲基苯丙胺；摇头丸）的娱乐性使用者存在工作记忆和执行功能缺陷。反过来，这两种结构都与三段论推理表现有关。对22名摇头丸使用者（平均年龄 = 21.36岁）和26名非摇头丸使用者对照组（平均年龄 = 21.31岁）进行了不同难度三段论以及工作记忆和执行功能测量的测试。摇头丸使用者在三段论推理方面明显受损，在作者控制了其他药物的使用后，这种影响仍然显著。然而，在控制了工作记忆广度的组间差异后，与摇头丸相关的差异降至统计学意义以下。结果与以下可能性一致，即摇头丸使用者执行功能方面与摇头丸相关的缺陷导致推理表现受损。
Zotero 插件