鼻咽癌患者分泌性中耳炎的激光鼓膜切开术
Laser myringotomy for otitis media with effusion in nasopharyngeal carcinoma patients.
作者信息
Hwang Chung-Feng, Chien Chih-Yen, Lin Hsin-Ching, Peng Jyh-Ping, Chang Hsueh-Wen, Su Chih-Ying
机构信息
Department of Otolaryngology, Chang Gung University, Kaohsiung Chang Gung Memorial Hospital, Taiwan.
出版信息
Otolaryngol Head Neck Surg. 2005 Jun;132(6):924-7. doi: 10.1016/j.otohns.2005.01.042.
OBJECTIVE
To evaluate the effectiveness of laser myringotomy in otitis media with effusion (OME) in patients with nasopharyngeal carcinoma (NPC).
STUDY DESIGN AND SETTING
Laser myringotomy was performed with a CO 2 laser otoscope in 53 NPC patients (68 ears) and 32 non-NPC patients (37 ears). All patients had a history of OME.
RESULTS
In the NPC group, 40% of ears developed persistent perforation, 37% had recurrent OME, and 23% were free of disease. In the non-NPC group, only 3% of ears developed persistent perforation, and 43% were free of disease. Significant differences in perforation and disease-free state were evident between the 2 groups. Tumor stage was found to be a significant determining factor for clinical outcome in NPC group.
CONCLUSION
Laser myringotomy for NPC group carries a significantly higher risk of persistent perforation and lower rate of cure. This procedure may be considered for early staging NPC patients with serious OME symptoms.
目的
评估激光鼓膜切开术治疗鼻咽癌（NPC）患者分泌性中耳炎（OME）的有效性。
研究设计与地点
对53例NPC患者（68耳）和32例非NPC患者（37耳）使用二氧化碳激光耳镜进行激光鼓膜切开术。所有患者均有OME病史。
结果
在NPC组中，40%的耳朵出现持续性穿孔，37%复发OME，23%无疾病。在非NPC组中，仅3%的耳朵出现持续性穿孔，43%无疾病。两组之间在穿孔和无疾病状态方面存在显著差异。发现肿瘤分期是NPC组临床结果的一个重要决定因素。
结论
NPC组进行激光鼓膜切开术出现持续性穿孔的风险显著更高，治愈率更低。对于有严重OME症状的早期NPC患者可考虑此手术。
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