[难治性水肿：考虑全身性毛细血管渗漏综合征]

[Refractory oedema: think about systemic capillary leak syndrome].

作者信息

Chiche L, Donati S, Granier I, Arnal J-M, Durand-Gasselin J

机构信息

Service de réanimation polyvalente, hôpital Font-pré, 1208, avenue du Colonel-Picot, 83056 Toulon, France.

出版信息

Ann Fr Anesth Reanim. 2005 Oct;24(10):1291-3. doi: 10.1016/j.annfar.2005.05.001. Epub 2005 Jun 9.

DOI:10.1016/j.annfar.2005.05.001

PMID:15949915

Abstract

Systemic Capillary Leak Syndrome (SCLS) is a rare and recently discovered disease. The diagnosis must be evoked in front of an hypovolaemic shock associated with a refractory anasarca. We report an observation of SCLS and then discuss the diagnostic and therapeutic difficulties. SCLS is diagnosed when a patient meet a compatible clinical situation with an hypoalbuminemia in spite of relative hemoconcentration. Evidence of a monoclonal gammapathy constitute an additional clue.

摘要

系统性毛细血管渗漏综合征（SCLS）是一种罕见且最近才被发现的疾病。在出现与难治性全身性水肿相关的低血容量性休克时，必须考虑到该诊断。我们报告一例SCLS病例，并讨论其诊断和治疗难点。当患者尽管存在相对血液浓缩但仍出现符合低白蛋白血症的临床情况时，可诊断为SCLS。单克隆丙种球蛋白病的证据是另一条线索。