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清醒状态下单阶段双侧胸腔镜交感神经切除术治疗手掌多汗症:一种安全的门诊手术。

Awake one stage bilateral thoracoscopic sympathectomy for palmar hyperhidrosis: a safe outpatient procedure.

作者信息

Elia Stefano, Guggino Gianluca, Mineo Davide, Vanni Gianluca, Gatti Antonello, Mineo Tommaso Claudio

机构信息

Division of Thoracic Surgery, Tor Vergata School of Medicine, Policlinico Tor Vergata University, Rome, Italy.

出版信息

Eur J Cardiothorac Surg. 2005 Aug;28(2):312-7; discussion 317. doi: 10.1016/j.ejcts.2005.03.046.

Abstract

OBJECTIVE

To verify the feasibility and compare the results of thoracoscopic sympathectomy under local anaesthesia (LA) and spontaneous breathing vs. general anaesthesia (GA) with one-lung ventilation.

METHODS

Two groups of consecutive patients underwent one stage bilateral T2-T3 thoracoscopic sympathectomy under LA (n=15) and GA (n=30) by the same surgical team for treatment of primary palmar hyperhidrosis. The groups were homogeneous for relevant demographic, physiological and clinical data, including pulmonary function. In both groups, patient's satisfaction was evaluated 24h after surgery by a simple interview and scored into five grades (1=very poor to 5=excellent), while quality of life (QOL) was evaluated by SF-36 and Nottingham's Health Profile questionnaires before and 6 months after surgery. A cost comparison between groups concerning devices, drugs, global in operating room time, medical personnel and hospital stay was also carried out.

RESULTS

No operative mortality was recorded. The overall in operating room time for the whole bilateral procedure under LA was 63.55+/-10.58 vs. 86.05+/-5.75 under GA (P<0.01) and temperature increased in all patients from a baseline of 25.42+/-0.56 up to 32.15+/-0.84 degrees C. All patients undergone LA were discharged the same day after a chest roentgenogram and a short stay in the outpatient clinic. Among them three patients (20%) experienced a minimal (<30%) pneumothorax that required no treatment, while five (33.3%) had a trunk compensatory sweating that spontaneously resolved on the long run. Patients undergoing GA were discharged after a mean stay of 1.38+/-0.6 days. Among these, eight (26.6%) had prolonged trunk compensatory sweating that did not persist longer than 3 months. At a follow-up of 7.16+/-2.97 months, QOL was significantly improved with no difference between groups. The overall rate of satisfaction was greater in the LA group (P<0.05).

CONCLUSIONS

In our study, awake one stage bilateral thoracoscopic sympathectomy for palmar hyperhidrosis could be safely and effectively performed as an outpatient procedure in patients refusing GA. Postoperative quality of life was equal to that in patients undergone the same procedure under GA, while patient satisfaction was better and cost were significantly reduced.

摘要

目的

验证局部麻醉(LA)下自主呼吸行胸腔镜交感神经切除术与全身麻醉(GA)下单肺通气的可行性,并比较两者的结果。

方法

两组连续患者由同一手术团队分别在LA(n = 15)和GA(n = 30)下行一期双侧T2 - T3胸腔镜交感神经切除术,用于治疗原发性手掌多汗症。两组在相关人口统计学、生理学和临床数据(包括肺功能)方面具有同质性。两组均在术后24小时通过简单访谈评估患者满意度,并分为五个等级(1 = 非常差至5 = 优秀),同时在手术前和术后6个月通过SF - 36和诺丁汉健康状况问卷评估生活质量(QOL)。还对两组在设备、药物、手术室总时间、医务人员和住院时间方面的费用进行了比较。

结果

未记录到手术死亡病例。LA下双侧手术的总手术室时间为63.55±10.58分钟,而GA下为86.05±5.75分钟(P < 0.01),所有患者体温从基线的25.42±0.56℃升高至32.15±0.84℃。所有接受LA的患者在胸部X线检查后及在门诊短暂停留后于同日出院。其中3例患者(20%)出现轻微(<30%)气胸,无需治疗,而5例(33.3%)有躯干代偿性出汗,最终自行缓解。接受GA的患者平均住院1.38±0.6天后出院。其中8例(26.6%)有持续性较长的躯干代偿性出汗,但持续时间不超过3个月。在7.16±2.97个月的随访中,QOL显著改善,两组间无差异。LA组的总体满意度更高(P < 0.05)。

结论

在我们的研究中,对于拒绝GA的患者,清醒状态下一期双侧胸腔镜交感神经切除术治疗手掌多汗症可作为门诊手术安全有效地进行。术后生活质量与接受GA行相同手术的患者相当,而患者满意度更高,费用显著降低。

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