1-Amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid as a Tic mimetic: application in the synthesis of potent human melanocortin-4 receptor selective agonists.
作者信息
Bakshi Raman K, Hong Qingmei, Olson J T, Ye Zhixiong, Sebhat Iyassue K, Weinberg David H, MacNeil Tanya, Kalyani Rubana N, Tang Rui, Martin William J, Strack Alison, McGowan Erin, Tamvakopoulos Constantin, Miller Randy R, Stearns Ralph A, Tang Wei, Maclntyre D Euan, van der Ploeg Lex H T, Patchett Arthur A, Nargund Ravi P
机构信息
Department of Medicinal Chemistry, Merck Research Laboratories, Rahway, NJ 07065-0900, USA.
出版信息
Bioorg Med Chem Lett. 2005 Jul 15;15(14):3430-3. doi: 10.1016/j.bmcl.2005.05.012.
PMID:15951175
Abstract
The discovery of 1-amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid analogs as potent human melanocortin-4 selective agonists is described.
摘要
Zotero 插件