使用低剂量技术评估特发性间质性肺炎的定量CT指标
Evaluation of quantitative CT indexes in idiopathic interstitial pneumonitis using a low-dose technique.
作者信息
Sverzellati Nicola, Zompatori Maurizio, De Luca Giovanni, Chetta Alfredo, Bnà Claudio, Ormitti Francesca, Cobelli Rocco
机构信息
Department of Clinical Sciences, Section of Radiology, University of Parma, Via Rasori, 10 43100 Parma, Italy.
出版信息
Eur J Radiol. 2005 Dec;56(3):370-5. doi: 10.1016/j.ejrad.2005.05.012. Epub 2005 Jun 22.
OBJECTIVE
To evaluate and compare histogram features (mean lung attenuation, skewness, kurtosis) of low-dose and standard-dose CT in a group of patients affected by idiopathic interstitial pneumonitis.
METHODS
We analyzed 16 patients affected by idiopathic interstitial pneumonitis. Spiral whole lung thin-section CT acquisition at standard dose (100 mAs) and three additional low-dose (50 mAs) CT images were obtained. After obtained frequency histograms, mean lung attenuation (MLA), skewness and kurtosis and three range of density (-700/-200 HU; -700/-400 HU; -500/-200 HU) of the standard-and low-dose thin-section CT scans were analyzed and compared.
RESULTS
The parameters obtained with low-dose and standard-dose spiral CT were correlated in a highly significant manner and were equivalent (p<0.01). The greatest correlation was found between standard-and low-dose kurtosis and standard and low-dose -700/-400 HU subrange of density (r=0.92; p<0.0001).
CONCLUSIONS
Our results prove that a quantitative CT objective evaluation in lung fibrosis can be successfully obtained with low-dose spiral CT, with reduced mA.
目的
评估并比较一组特发性间质性肺炎患者低剂量和标准剂量CT的直方图特征（平均肺衰减、偏度、峰度）。
方法
我们分析了16例特发性间质性肺炎患者。获取了标准剂量（100 mAs）的螺旋全肺薄层CT图像以及另外三张低剂量（50 mAs）CT图像。在获得频率直方图后，分析并比较了标准剂量和低剂量薄层CT扫描的平均肺衰减（MLA）、偏度、峰度以及三个密度范围（-700/-200 HU；-700/-400 HU；-500/-200 HU）。
结果
低剂量和标准剂量螺旋CT获得的参数具有高度显著的相关性且相当（p<0.01）。标准剂量和低剂量峰度以及标准剂量和低剂量-700/-400 HU密度子范围之间的相关性最强（r=0.92；p<0.0001）。
结论
我们的结果证明，使用低剂量螺旋CT并降低毫安数，可以成功获得肺纤维化的定量CT客观评估。
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