Hasegawa Mitsuhiro, Fujisawa Hironori, Hayashi Yutaka, Yamashita Junkoh, Suzuki Masayuki, Matsui Osamu
Department of Neurosurgery, Division of Neuroscience, Graudate School of Medical Science, Kanazawa University, Kanazawa, Japan.
J Clin Neurosci. 2005 Jun;12(5):548-52. doi: 10.1016/j.jocn.2004.08.012.
The aim of this study is to investigate the efficacy of dynamic computed tomography (CT) during selective angiography (CT-arteriography) of orbital tumors in the evaluation of intratumoral vascular anatomy, feeding artery territory, and histological diagnosis. Among 35 consecutive cases with various orbital lesions, those cases showing tumor staining or pooling of the contrast medium on digital subtraction angiography (DSA) were evaluated by CT-arteriography (n = 14). The information obtained by CT-arteriography was compared with that provided by enhanced MRI (n = 31) and dynamic MRI (n = 21), in which the contrast medium was injected intravenously. In addition to the visualization of fine vascular anatomy, CT-arteriography emphasized areas of nodular enhancement and non-enhancing cystic/necrotic components as well as the intratumoral feeding arteries. Patterns of CT-arteriography were categorized into three subgroups: homogeneous enhancement (benign lymphoid lesion), partial enhancement (schwannomas and carcinomas), and patchy multinodular enhancement (specific for cavernous angiomas). In addition, CT-arteriography with selective arterial catheterization clearly delineated the feeding artery territories. CT-arteriography, with a minimal dose of contrast medium, can offer significant advantages over intravenously injected dynamic neuroimaging, and provides additional valuable preoperative information about the orbital tumor under investigation.
本研究的目的是探讨动态计算机断层扫描(CT)在眼眶肿瘤选择性血管造影(CT血管造影)中对肿瘤内血管解剖结构、供血动脉区域及组织学诊断评估的有效性。在连续35例患有各种眼眶病变的病例中,对数字减影血管造影(DSA)显示肿瘤染色或造影剂积聚的病例进行CT血管造影评估(n = 14)。将CT血管造影获得的信息与静脉注射造影剂的增强MRI(n = 31)和动态MRI(n = 21)提供的信息进行比较。除了能显示精细的血管解剖结构外,CT血管造影还能突出结节状强化区域、无强化的囊性/坏死成分以及肿瘤内供血动脉。CT血管造影模式可分为三个亚组:均匀强化(良性淋巴病变)、部分强化(神经鞘瘤和癌)和斑片状多结节强化(海绵状血管瘤特有)。此外,选择性动脉插管的CT血管造影能清晰勾勒出供血动脉区域。CT血管造影使用最小剂量的造影剂,与静脉注射动态神经成像相比具有显著优势,并能为所研究的眼眶肿瘤提供额外有价值的术前信息。