Yasuda Seiei, Shimada Hideo, Chino Osamu, Nishi Takayuki, Takechi Masahiko, Makuuchi Hiroyasu
Dept. of Surgery, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Gan To Kagaku Ryoho. 2005 Jun;32(6):877-81.
It is not uncommon that first lymph node involvement appears at a distant lymph node not at a nearest node from the primary lesion in patients with esophageal cancer. Identification of the sentinel node, which permits the detection of the first draining node from a primary lesion, is expected to individualize the treatment of esophageal cancer. From our study in 23 patients with esophageal cancer using Tc-99 m tin colloids, the sentinel node concept seemed to be applicable to patients with esophageal cancer (-pT2). However, injection techniques and intraoperative probe searching for hot nodes are more difficult and uncertain in esophageal cancer compared to superficial cancers such as breast cancer and malignant melanoma. Further studies are necessary to reliably apply the sentinel node biopsy technique to patients with esophageal cancer.
在食管癌患者中,首个淋巴结转移出现在远离原发灶的远处淋巴结而非距离最近的淋巴结,这种情况并不少见。前哨淋巴结是指能够检测到来自原发灶的首个引流淋巴结,确定前哨淋巴结有望实现食管癌治疗的个体化。我们对23例食管癌患者使用锝-99m锡胶体进行研究,前哨淋巴结概念似乎适用于食管癌(-pT2)患者。然而,与乳腺癌和恶性黑色素瘤等浅表癌相比,食管癌的注射技术和术中用探头寻找热结节更加困难且不确定。有必要进一步开展研究,以便将前哨淋巴结活检技术可靠地应用于食管癌患者。