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“鼓掌征”有助于鉴别进行性核上性麻痹与额颞叶痴呆和帕金森病。

"Applause sign" helps to discriminate PSP from FTD and PD.

作者信息

Dubois B, Slachevsky A, Pillon B, Beato R, Villalponda J M, Litvan I

机构信息

INSERM U 610, Fédération de Neurologie, Hôpital de la Salpêtrière, Paris, France.

出版信息

Neurology. 2005 Jun 28;64(12):2132-3. doi: 10.1212/01.WNL.0000165977.38272.15.

Abstract

The "applause sign" is a simple test of motor control that helps to differentiate PSP from frontal or striatofrontal degenerative diseases. It was found in 0/39 controls, 0 of 24 patients with frontotemporal dementia (FTD), 0 of 17 patients with Parkinson disease (PD), and 30/42 patients with progressive supranuclear palsy (PSP). It discriminated PSP from FTD (p < 0.001) and PD (p < 0.00). The "three clap test" correctly identified 81.8% of the patients in the comparison PSP and FTD and 75% of the patients in the comparison of PSP and PD.

摘要

“鼓掌征”是一种简单的运动控制测试,有助于将进行性核上性麻痹(PSP)与额叶或纹状体额叶变性疾病区分开来。在39名对照者中未发现该体征,24例额颞叶痴呆(FTD)患者中为0例,17例帕金森病(PD)患者中为0例,而42例进行性核上性麻痹(PSP)患者中有30例出现该体征。它能将PSP与FTD(p<0.001)及PD(p<0.00)区分开来。在PSP与FTD的比较中,“三拍测试”正确识别出了81.8%的患者;在PSP与PD的比较中,正确识别出了75%的患者。

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