Gol Mert, Guclu Serkan, Demir Ahmet, Erata Yakup, Demir Namik
Department of Obstetrics and Gynecology, Dokuz Eylül University Hospital, Izmir, Turkey.
Arch Gynecol Obstet. 2005 Dec;273(2):90-2. doi: 10.1007/s00404-005-0036-8. Epub 2005 Jul 1.
Maternal serum human chorionic gonadotropin (MshCG) levels are higher in pregnant women with female fetuses than in pregnant women with male fetuses in the third trimester of pregnancy. Our aim was to examine the effect of fetal sex on MshCG levels throughout the pregnancy.
Twenty-nine uncomplicated pregnancies (14 had male fetus and 15 had female fetus) were included in the study. MshCG levels were measured four times between 8-12, 14-18, 24-28 and 32-36 weeks of pregnancy.
MshCG levels were significantly higher in both sexes between 8-12 weeks than the other three measurement periods. At 8-12 and 14-18 weeks measurements, there were no sex related differences in the MshCG levels. At 24-28 (P<0.004) and 32-36 (P<0.001) weeks MshCG levels were significantly higher in pregnancies bearing female fetuses than those bearing male fetuses.
Fetal gender has a significant effect on MshCG levels in the third trimester of pregnancy. Accordingly, no correlation seems to exist in the first and second trimesters.
在妊娠晚期,怀有女胎的孕妇血清人绒毛膜促性腺激素(MshCG)水平高于怀有男胎的孕妇。我们的目的是研究胎儿性别在整个孕期对MshCG水平的影响。
本研究纳入了29例无并发症的妊娠病例(14例怀有男胎,15例怀有女胎)。在妊娠8 - 12周、14 - 18周、24 - 28周和32 - 36周这四个时间段测量MshCG水平。
在8 - 12周时,两性的MshCG水平均显著高于其他三个测量时间段。在8 - 12周和14 - 18周测量时,MshCG水平不存在与性别相关的差异。在24 - 28周(P<0.004)和32 - 36周(P<0.001)时,怀有女胎的孕妇的MshCG水平显著高于怀有男胎的孕妇。
胎儿性别对妊娠晚期的MshCG水平有显著影响。因此,在妊娠早期和中期似乎不存在相关性。