Mithöfer Kai, Minas Tom, Peterson Lars, Yeon Howard, Micheli Lyle J
Cartilage Repair Center, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Am J Sports Med. 2005 Aug;33(8):1147-53. doi: 10.1177/0363546504274146. Epub 2005 Jul 6.
Limited information exists about the treatment of full-thickness articular cartilage lesions of the knee in adolescent athletes.
To evaluate the functional outcome and athletic activity after articular cartilage repair in the knees of adolescent athletes.
Case series; Level of evidence, 4.
Twenty adolescent athletes with full-thickness articular cartilage lesions of the knee were treated with autologous chondrocyte transplantation. Functional outcome was evaluated by subjective patient outcome rating, knee activity scores, and level of athletic participation.
At a mean of 47 months after autologous chondrocyte transplantation, 96% of adolescents reported good or excellent results with significant increases in postoperative Tegner activity scores and Lysholm scores. Ninety-six percent returned to high-impact sports and 60% to an athletic level equal or higher than that before knee injury. Return to preinjury sports correlated with shorter preoperative symptoms and a lower number of prior operations. All adolescents with preoperative symptoms < or =12 months returned to preinjury-level athletics, compared to 33% with preoperative intervals longer than 12 months.
Treatment of full-thickness articular injuries of the knee in adolescent athletes with autologous chondrocyte transplantation yields a high rate of functional success at a mean follow-up of 47 months. The rate of return to demanding athletic activities is higher in cases in which the preoperative duration of symptoms is 12 months or less.
关于青少年运动员膝关节全层关节软骨损伤的治疗,现有信息有限。
评估青少年运动员膝关节软骨修复后的功能结果和体育活动情况。
病例系列;证据等级,4级。
20名患有膝关节全层关节软骨损伤的青少年运动员接受了自体软骨细胞移植治疗。通过患者主观结果评分、膝关节活动评分和体育参与水平评估功能结果。
自体软骨细胞移植后平均47个月时,96%的青少年报告结果良好或优秀,术后Tegner活动评分和Lysholm评分显著提高。96%的患者恢复了高强度运动,60%的患者恢复到与膝关节损伤前相当或更高的运动水平。恢复到伤前运动水平与术前症状持续时间较短和既往手术次数较少相关。所有术前症状≤12个月的青少年都恢复到了伤前水平的运动,而术前间隔超过12个月的患者中这一比例为33%。
对青少年运动员膝关节全层关节损伤进行自体软骨细胞移植治疗,在平均47个月的随访中功能成功率较高。术前症状持续时间为12个月或更短的情况下,恢复到高要求体育活动的比例更高。