Iacob Gh, Ciochină Al D, Herea D D, Dimitriu Cristina, Chiruţă Roxana, Vieru Cristina, Stratone Ana
Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Bioinginerie Medicală.
Rev Med Chir Soc Med Nat Iasi. 2004 Oct-Dec;108(4):924-7.
The red cells exhibit a proper magnetism due to hemoglobin. In a prototype of high gradient magnetic separator equipped with an ordered ferromagnetic matrix, a set of experiments with blood to determine the influence of the process parameters on the efficiency of the erythrocytes capture was realized. Dependent on the values of the magnetic induction (1.76-2.01 T), average blood flow velocity through the matrix (0.55-1.1 mm/s), and stationary time in the matrix, different values of concentration for the red cells in the matrix were obtained. For tests realized with integral blood, the concentration was approximately 20%, while for tests with diluted blood the concentration fluctuated from 14.51% to 29.90%. A blood recirculation through the matrix led to a concentration of 37.86%. The magnetic separation method permits an acceptable red cells concentration, without apparent destructive effects on the cells.
红细胞由于血红蛋白而呈现出一定的磁性。在配备有序铁磁基质的高梯度磁选机原型中，进行了一系列血液实验，以确定工艺参数对红细胞捕获效率的影响。根据磁感应强度值（1.76 - 2.01 T）、通过基质的平均血流速度（0.55 - 1.1 mm/s）以及在基质中的停留时间，获得了基质中红细胞的不同浓度值。对于全血测试，浓度约为20%，而对于稀释血液测试，浓度在14.51%至29.90%之间波动。血液通过基质循环导致浓度达到37.86%。磁分离方法可实现可接受的红细胞浓度，且对细胞无明显破坏作用。
