Roos E J, Van Eijkeren M A, Boon T A, Heintz A P M
Gynecological Oncological Center, University Medical Center Utrecht, Utrecht, The Netherlands.
Int J Gynecol Cancer. 2005 Jul-Aug;15(4):624-9. doi: 10.1111/j.1525-1438.2005.00118.x.
Pelvic exenteration is used as therapeutic option for advanced or recurrent cancer in the pelvis. We determined the complications of and the survival after pelvic exenteration. The study was performed as a retrospective cohort (n = 62) study from January 1, 1989, until January 1, 2000. Descriptive statistics were used. Survival was estimated according to the Kaplan-Meier life table. The operative mortality was 1.6%. Seventy-five percent of the patients had postoperative complications of which ileus and urinary tract infection were the most common. Late complications occurred in 83% of the patients. Recurrent disease was observed in 38% of the women, whereas 50% had died on January 1, 2000. Five-years disease-free and overall survival were 42% (confidence interval [CI] +/- 14%) and 46% (CI +/- 14%), respectively. Elderly patients (> 70 years old) do not experience more complications. Despite considerable morbidity, pelvic exenteration is a therapeutic option for survival, even for patients of 70 years and older.
盆腔脏器清除术被用作盆腔晚期或复发性癌症的治疗选择。我们确定了盆腔脏器清除术的并发症及术后生存率。该研究为回顾性队列研究（n = 62），时间跨度从1989年1月1日至2000年1月1日。采用描述性统计方法。根据Kaplan-Meier生存表估计生存率。手术死亡率为1.6%。75%的患者有术后并发症，其中肠梗阻和尿路感染最为常见。83%的患者出现晚期并发症。38%的女性患者出现疾病复发，而到2000年1月1日，50%的患者已经死亡。五年无病生存率和总生存率分别为42%（置信区间[CI]±14%）和46%（CI±14%）。老年患者（>70岁）并未出现更多并发症。尽管有相当高的发病率，但盆腔脏器清除术仍是一种可提高生存率的治疗选择，即使对于70岁及以上的患者也是如此。
