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角膜组织的航空运输:本地供体角膜与跨大西洋供体角膜的经验比较

Air transportation of corneal tissue: experience with local compared to transatlantic donor corneas.

作者信息

Varssano David, Russ Vivian, Linhart Yifat, Lazar Moshe

机构信息

Department of Ophthalmology, Tel Aviv Medical Center and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Cornea. 2005 Aug;24(6):674-7. doi: 10.1097/01.ico.0000157419.11448.59.

Abstract

PURPOSE

To compare the outcome of corneas obtained at the same hospital in which they were transplanted (group 1) to that of corneas obtained in the United States and grafted in Israel (group 2).

METHODS

One hundred twenty-six patients undergoing corneal grafting in Israel during the years 1995 to 1998 were included in a retrospective, nonrandomized clinical trial. Group 1 included 31 procedures, and group 2 included 95. Data regarding preoperative condition, tissue characteristics, and postoperative outcome were collected from hospital charts. Statistically significant difference between groups was considered as P < 0.05.

RESULTS

Follow-up time was 796 +/- 523 days for group 1 (mean +/- SD) and 815 +/- 510 days for group 2. Donor age and gender, recipient age and gender, graft size, and length of follow-up were similar. Time from preservation to transplantation was longer for group 2 (8.8 +/- 2.29 days) compared with in group 1 (3.13 +/- 2.38 days). Graft clarity was similar between groups 1 and 2 at 1 year (79% versus 71%) and at last follow-up visit (57% versus 62%). Visual acuity, intraocular pressure, and incidence of complications such as rejection (32% versus 38%), failure (35% versus 28%), secondary glaucoma (35% versus 43%), corneal ulcer (13% versus 6%), and regrafts (13% versus 7%) showed no difference between the groups.

CONCLUSIONS

Air transport of corneal tissue, including loss of time due to travel and handling, did not compromise corneal transplantation success rate.

摘要

目的

比较在同一所进行角膜移植手术的医院获取的角膜(第1组)与在美国获取并在以色列进行移植的角膜(第2组)的移植效果。

方法

1995年至1998年期间在以色列接受角膜移植手术的126例患者纳入一项回顾性、非随机临床试验。第1组包括31例手术,第2组包括95例。从医院病历中收集术前情况、组织特征和术后结果的数据。组间差异有统计学意义定义为P<0.05。

结果

第1组的随访时间为796±523天(平均±标准差),第2组为815±510天。供体年龄和性别、受体年龄和性别、移植片大小及随访时间相似。第2组从保存到移植的时间(8.8±2.29天)比第1组(3.13±2.38天)长。第1组和第2组在1年时(79%对71%)以及最后一次随访时(57%对62%)移植片透明度相似。视力、眼压以及排斥反应(32%对38%)、移植失败(35%对28%)、继发性青光眼(35%对43%)、角膜溃疡(13%对6%)和再次移植(13%对7%)等并发症的发生率在两组间无差异。

结论

角膜组织航空运输,包括因运输和处理导致的时间损失,并未影响角膜移植成功率。

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