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马的遗传性骨骼肌疾病。综述。

Hereditary skeletal muscle diseases in the horse. A review.

作者信息

Nollet H, Deprez P

机构信息

Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, University of Ghent, Merelbeke, Belgium.

出版信息

Vet Q. 2005 Jun;27(2):65-75. doi: 10.1080/01652176.2005.9695187.

Abstract

Since riders nowadays are expecting the highest level of performance from their horses, muscular disorders therefore represent a major problem for the equine athlete. A lot of research has been done to identify muscular disorders and their etiopathogenesis. Both acquired and inherited forms of muscle diseases have been described. In this review only the latter forms will be mentioned. Major signs of all muscle disorders are muscular stiffness, cramping or pain, muscular fasciculations, muscular atrophy and exercise intolerance. Muscle biopsies can help to identify the cause of rhabdomyolysis or muscular atrophy. However, especially in hereditary muscular diseases, a lot of questions are still to be answered. Increasing knowledge of the etiopathogenesis and newer diagnostic tests may lead to a more accurate diagnosis of the individual diseases in future.

摘要

由于如今骑手们期望他们的马匹具备最高水平的表现,因此肌肉疾病对马类运动员来说是一个重大问题。为了识别肌肉疾病及其病因发病机制,已经开展了大量研究。肌肉疾病的后天性和遗传性形式均已被描述。在本综述中,仅会提及后者。所有肌肉疾病的主要症状包括肌肉僵硬、痉挛或疼痛、肌肉纤维震颤、肌肉萎缩和运动不耐受。肌肉活检有助于确定横纹肌溶解或肌肉萎缩的原因。然而,尤其是在遗传性肌肉疾病方面,仍有许多问题有待解答。对病因发病机制的了解不断增加以及更新的诊断测试可能会在未来带来对个体疾病更准确的诊断。

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