Saraph Vinay J, Bach Christian M, Krismer Martin, Wimmer Cornelius
Department of Orthopaedic Surgery, Leopold Franzens University, Innsbruck, Austria.
Spine (Phila Pa 1976). 2005 Jul 15;30(14):1594-601. doi: 10.1097/01.brs.0000170299.48246.28.
A retrospective cohort study.
To evaluate anterior strut grafts in spinal fusion for thoracic/thoracolumbar kyphosis.
Autologous strut grafts harvested from the fibula, iliac crest, and rib are frequently used for treating severe kyphosis and kyphoscoliosis. However, a majority of the studies have presented mixed patient populations kyphosis and/or scoliosis, treated either with anterior or anteroposterior fusion. Very few reports have presented an evaluation of autologous strut grafts for anterior fusion with posterior instrumentation for the treatment of kyphotic deformities.
A total of 23 patients comprised the study. Diagnosis was granulomatous infection (9 patients), congenital (6), posttraumatic (4), neurofibromatosis (1), ankylosing spondylitis (1), Scheuermann disease (1), and plasmacytoma of the vertebral body with pathologic fracture (1). Average age at surgery was 41 years (range 6-77). Indication for surgery was pain with or without progression in 15 patients and additional progressive neurologic deficit in the other 8. Anterior strut grafts consisted of the autologous fibula (9 patients), iliac (10), fibula and ribs (2), fibula and iliac (1), and fibula, iliac, and ribs (1). The fusion areas were thoracic (11 patients), thoracolumbar (11), and cervicothoracic (1). Anterior decompression was performed in 8 patients because of the presence of neurologic symptoms caused by cord compression. Dorsal fusion was performed in all patients with third-generation systems.
Average 4.2 vertebrae were fused anteriorly. Mean follow-up bracing time was 9.7 months. Average kyphosis measured 50.9 degrees before surgery and 32.5 at a mean follow-up of 4.5 years (P < 0.0001). No graft breakages were noted at final follow-up. Solid fusion was achieved in all patients. No donor site complications were observed. Of the 8 patients presenting with neurologic deficits, 4 had full recovery, 3 had partial recoveries, and 1 had no improvement. Loss of postoperative correction > 5 degrees was observed in 3 patients. At final follow-up, 3 patients complained of occasional pain, and 1 complained of pain when lying on the back, particularly on hard surfaces.
Adequate correction was maintained throughout an average follow-up of 4.5 years, and solid fusion was obtained in all patients. Anterior strut grafts, supplemented with posterior fusion with instrumentation provide a good treatment alternative for the treatment of kyphosis deformity of the spine as a result of various etiologies.
一项回顾性队列研究。
评估前路支撑植骨在胸段/胸腰段脊柱后凸畸形脊柱融合术中的应用。
取自腓骨、髂嵴和肋骨的自体支撑植骨常用于治疗严重脊柱后凸和脊柱侧凸后凸畸形。然而,大多数研究纳入的患者群体混合了脊柱后凸和/或脊柱侧凸,采用前路或前后路联合融合术进行治疗。极少有报告对自体支撑植骨联合后路器械辅助前路融合治疗脊柱后凸畸形进行评估。
本研究共纳入23例患者。诊断包括肉芽肿性感染(9例)、先天性(6例)、创伤后(4例)、神经纤维瘤病(1例)、强直性脊柱炎(1例)、休门氏病(1例)以及椎体浆细胞瘤伴病理性骨折(1例)。手术时的平均年龄为41岁(范围6 - 77岁)。手术指征为15例患者伴有疼痛且有或无病情进展,另外8例患者伴有进行性神经功能缺损。前路支撑植骨包括自体腓骨(9例)、髂骨(10例)、腓骨和肋骨(2例)、腓骨和髂骨(1例)以及腓骨、髂骨和肋骨(1例)。融合部位为胸段(11例)、胸腰段(11例)和颈胸段(1例)。8例因脊髓受压导致神经症状的患者接受了前路减压。所有患者均采用第三代系统进行后路融合。
前路平均融合4.2个椎体。平均随访支具佩戴时间为9.7个月。术前平均脊柱后凸角度为50.9度,平均随访4.5年时为32.5度(P < 0.0001)。末次随访时未发现植骨断裂。所有患者均实现了坚固融合。未观察到供区并发症。8例有神经功能缺损的患者中,4例完全恢复,3例部分恢复,1例无改善。3例患者术后矫正丢失>5度。末次随访时,3例患者偶尔抱怨疼痛,1例患者仰卧时疼痛,尤其是在硬表面上。
在平均4.5年的随访期内维持了充分的矫正,所有患者均获得了坚固融合。前路支撑植骨联合后路器械辅助融合为治疗各种病因导致的脊柱后凸畸形提供了一种良好的治疗选择。