维拉帕米治疗家兔实验性高血压时心肌血液供应的变化
Changes in myocardial blood supply during experimental hypertension treated with verapamil in rabbits.
作者信息
Frolov V A, Drozdova G A, Rieger P, Blagonravov M
机构信息
Department of Pathological Physiology, Russian University of People Friendship, Moscow.
出版信息
Bull Exp Biol Med. 2005 Mar;139(3):277-8. doi: 10.1007/s10517-005-0270-x.
Rabbit hearts were studied at different periods of experimental arterial hypertension and its treatment with verapamil. Morphological study revealed a progressive decrease in the number of capillaries per unit mass during the development of myocardial hypertrophy in hypertensive hearts. In hypertensive animals treated with verapamil the density of capillaries in both ventricles did not decrease, but verapamil injected to intact animals sharply decreased this parameter.
对处于实验性动脉高血压不同阶段及其维拉帕米治疗阶段的兔心脏进行了研究。形态学研究显示，在高血压性心脏心肌肥大发展过程中，单位质量的毛细血管数量逐渐减少。在用维拉帕米治疗的高血压动物中，两个心室的毛细血管密度并未降低，但向正常动物注射维拉帕米会使这一参数急剧下降。
Zotero 插件