Kailas N A, Sifakis S, Koumantakis E
Department of Obstetrics and Gynecology, University of Crete, Heraklion, Greece.
Eur J Contracept Reprod Health Care. 2005 Mar;10(1):19-25. doi: 10.1080/13625180400020861.
Perimenopause marks the transition from normal ovulation to anovulation and ultimately to permanent loss of ovarian function. Fecundity, the average monthly probability of conception, declines by half as early as the mid-forties, however women during the perimenopause still need effective contraception. Issues arising at this period such as menstrual cycle abnormalities, vasomotor instability, the need for osteoporosis and cardiovascular disease prevention, as well as the increased risk of gynecological cancer, should be taken into consideration before the initiation of a specific method of contraception. Various contraceptive options may be offered to perimenopausal women, including oral contraceptives, tubal ligation, intrauterine devices, barrier methods, hormonal injectables and implants. Recently, new methods of contraception have been introduced presenting high efficacy rates and minor side-effects, such as the monthly injectable system, the contraceptive vaginal ring and the transdermal contraceptive system. However, these new methods have to be further tested in perimenopausal women, and more definite data are required to confirm their advantages as effective contraceptive alternatives in this specific age group. The use of the various contraceptive methods during perimenopause holds special benefits and risks that should be carefully balanced, after a thorough consultation and according to each woman's contraceptive needs.
围绝经期标志着从正常排卵向无排卵的转变,并最终导致卵巢功能永久性丧失。受孕能力,即每月平均受孕概率,早在四十多岁时就会减半,然而围绝经期女性仍需要有效的避孕措施。在开始采用特定避孕方法之前,应考虑这一时期出现的问题,如月经周期异常、血管舒缩不稳定、预防骨质疏松症和心血管疾病的需求,以及妇科癌症风险增加等。可以为围绝经期女性提供多种避孕选择,包括口服避孕药、输卵管结扎、宫内节育器、屏障法、激素注射剂和植入剂。最近,已引入了一些避孕新方法,这些方法具有高效和轻微副作用的特点,如每月注射系统、避孕阴道环和经皮避孕系统。然而,这些新方法必须在围绝经期女性中进一步测试,并且需要更确切的数据来证实它们作为这一特定年龄组有效避孕替代品的优势。在围绝经期使用各种避孕方法有特殊的益处和风险,在进行全面咨询并根据每位女性的避孕需求后,应仔细权衡这些利弊。