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[乳糜泻伴发肠T细胞淋巴瘤。病例报告]

[Intestinal T cell lymphoma in coeliac disease. A case report].

作者信息

Ayadi-Kaddour Aïda, Chelly-Enneifer Inès, Goutallier-Ben Fadhel Carole, Saïgi Essia, Gharbi Lassad, Lahmar-Boufaroua Ahlem, Ben Sassi Lotfi, Khalfallah Med Tahar, Mzabi-Regaya Sabah

机构信息

Service d'anatomie et de cytologie pathologiques, Hôpital Mongi Slim, La Marsa, Tunisie.

出版信息

Tunis Med. 2005 May;83(5):311-4.

Abstract

Primary intestinal T-cell lymphomas account for about 5% of all primary gastrointestinal lymphomas and are mostly associated with coeliac disease. Intestinal lymphomas are usually discovered during the 4th to 5th decade and constitute an exceptional complication of coeliac disease. This lymphoma is generally a high grade pleomorphic cell lymphoma with large cells. Our case concerned a 30 year old woman with a history of coeliac disease who developed a gastro-enteromesenteric lymphoma. Anatomopathological and immunohistochemical analysis showed an enteropathy associated T-cell lymphoma. We suggest that patients with coeliac disease unresponsive to a gluten free diet or with deteriorating clinical condition be investigated for complications such as enteropathy associated T-cell lymphoma. It is also important to avoid this complication by detecting asymptomatic form of coeliac disease that needs a gluten-free diet.

摘要

原发性肠道T细胞淋巴瘤约占所有原发性胃肠道淋巴瘤的5%,且大多与乳糜泻相关。肠道淋巴瘤通常在40至50岁时被发现,是乳糜泻的一种罕见并发症。这种淋巴瘤一般是伴有大细胞的高级别多形性细胞淋巴瘤。我们的病例是一名30岁有乳糜泻病史的女性,她患上了胃肠系膜淋巴瘤。解剖病理学和免疫组织化学分析显示为肠病相关T细胞淋巴瘤。我们建议,对无麸质饮食无反应或临床状况恶化的乳糜泻患者,应排查诸如肠病相关T细胞淋巴瘤等并发症。通过检测需要无麸质饮食的无症状乳糜泻形式来避免这种并发症也很重要。

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