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多通道超导量子干涉装置系统揭示人类听觉皮层的音频定位组织

Tonotopic organization of human auditory cortex revealed by multi-channel SQUID system.

作者信息

Yamamoto T, Uemura T, Llinás R

机构信息

Department of Otolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

出版信息

Acta Otolaryngol. 1992;112(2):201-4. doi: 10.1080/00016489.1992.11665404.

DOI:10.1080/00016489.1992.11665404
PMID:1604979
Abstract

A 14-channel SQUID (superconducting quantum interference device) system has been used to record the magnetic signal from the human brain in response to an auditory stimuli (750, 1,000, 1,250 and 1,500 Hz, 70, 76 and 82 dB SPL, 500 ms duration). Three individuals with normal hearing were studied. The locations of magnetic response at the latency of 70 ms (P70), 100 ms (N100) and 160 ms (P160) from the onset of the auditory stimulus were identified. The location for N100 response corresponded to the primary auditory cortex (area 41), where a clear tonotopic organization was demonstrated. The amplitopic organization was less evident. These results suggest a flow of auditory signals in the temporal lobe and tonotopic organization in the auditory cortex.

摘要

一个14通道的超导量子干涉装置(SQUID)系统被用于记录人类大脑对听觉刺激(750、1000、1250和1500赫兹,70、76和82分贝声压级,持续时间500毫秒)的磁信号。对三名听力正常的个体进行了研究。确定了从听觉刺激开始起70毫秒(P70)、100毫秒(N100)和160毫秒(P160)潜伏期时磁反应的位置。N100反应的位置对应于初级听觉皮层(41区),在那里显示出明显的音频拓扑组织。幅度拓扑组织不太明显。这些结果表明听觉信号在颞叶中的流动以及听觉皮层中的音频拓扑组织。

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