Izumihara Akifumi, Suzuki Michiyasu, Ishihara Tokuhiro
Department of Neurosurgery, Hikari City General Hospital, Hikari, Yamaguchi 743-0022, Japan.
Surg Neurol. 2005 Aug;64(2):160-4; discussion 164. doi: 10.1016/j.surneu.2004.09.010.
Many recent studies have analyzed clinical risk factors for the recurrence and extension of intracerebral hemorrhage. However, they have not been investigated in patients with lobar hemorrhage related to cerebral amyloid angiopathy (CAA).
We studied 40 surgically treated patients with lobar hemorrhage diagnosed histologically as being related to CAA. To determine clinical factors influencing the recurrence and hematoma size their clinical data (demographics, medical history, and radiographic and laboratory data) were examined retrospectively and subjected to multivariate analysis.
Twelve patients (30%) had recurrent lobar hemorrhage. Twenty-one patients had a small hematoma and 19 had a large hematoma. Hypertension was the only significant clinical factor influencing the recurrence of CAA-related lobar hemorrhage. There was no significant clinical factor influencing the hematoma size of CAA-related lobar hemorrhage.
The history of hypertension is associated with an increase in the recurrence of CAA-related lobar hemorrhage.
最近许多研究分析了脑出血复发和扩展的临床危险因素。然而，尚未在与脑淀粉样血管病（CAA）相关的叶状出血患者中进行调查。
我们研究了40例经手术治疗的叶状出血患者，经组织学诊断与CAA相关。为了确定影响复发和血肿大小的临床因素，对他们的临床数据（人口统计学、病史以及影像学和实验室数据）进行回顾性检查并进行多变量分析。
12例患者（30%）发生了复发性叶状出血。21例患者血肿较小，19例患者血肿较大。高血压是影响CAA相关叶状出血复发的唯一重要临床因素。没有显著的临床因素影响CAA相关叶状出血的血肿大小。
高血压病史与CAA相关叶状出血复发增加有关。
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