非渗出性年龄相关性黄斑变性全黄斑转位术后地理萎缩的快速复发

Rapid recurrence of geographic atrophy after full macular translocation for nonexudative age-related macular degeneration.

作者信息

Khurana Rahul N, Fujii Gildo Y, Walsh Alexander C, Humayun Mark S, de Juan Eugene, Sadda Srinivas R

机构信息

Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

出版信息

Ophthalmology. 2005 Sep;112(9):1586-91. doi: 10.1016/j.ophtha.2005.04.016.

DOI:10.1016/j.ophtha.2005.04.016

PMID:16051364

Abstract

OBJECTIVE

To report the recurrence of geographic atrophy (GA) in a patient with nonexudative age-related macular degeneration (AMD) after full macular translocation.

DESIGN

Observational case report.

METHODS

Review of the clinical, photographic, and angiographic records of a patient with GA who underwent full macular translocation.

MAIN OUTCOME MEASURES

Progression of GA.

RESULTS

A 73-year-old man with GA secondary to nonexudative AMD underwent a macular translocation with 360 peripheral retinectomy (MT 360) in his left eye. On postoperative month 4, fundus photography showed subtle alterations of the pigment underneath the translocated foveal region. On postoperative month 9, the visual acuity worsened to preoperative levels and there was frank retinal pigment epithelium atrophy involving the new macular region.

CONCLUSIONS

The rapid recurrence and development of GA in the translocated fovea after MT 360 raise new questions regarding the pathogenesis of GA. They also raise concerns regarding the use of MT 360 in the management of nonexudative AMD.

摘要