Rathmann W, Haastert B, Icks A, Giani G, Holle R, Meisinger C, Mielck A
Institute of Biometrics and Epidemiology, German Diabetes Center, Heinrich Heine University, Düsseldorf, Germany.
Eur J Public Health. 2005 Dec;15(6):627-33. doi: 10.1093/eurpub/cki037. Epub 2005 Jul 28.
Sex differences in the associations of socioeconomic status (SES) with prevalence of undiagnosed diabetes mellitus, impaired glucose tolerance (IGT) and known risk factors of type 2 diabetes mellitus were investigated in an elderly population.
Oral glucose tolerance tests were carried out in 1354 randomly selected subjects (697 men, 657 women) aged 55-74 years in the population-based KORA Survey 2000, Augsburg, Germany. Odds ratios (ORs) and 95% confidence intervals (CIs) for undiagnosed diabetes or IGT by education, occupation and income were estimated using logistic regression controlling for age, waist circumference, blood pressure, triglycerides, physical activity, smoking and alcohol intake.
All three SES variables were significantly inversely related to body mass index, waist circumference and low physical activity in women (P < 0.05). In men, these associations were weaker or absent. Using the lowest category as reference, occupational status was significantly associated with undiagnosed diabetes in women (adjusted OR 0.5; 95% CI 0.3-0.8) after controlling for risk factors in multivariate regression. The OR was also reduced with higher income in women (adjusted OR, diabetes: 0.7; 95% CI 0.5-1.03). Among men, no significant relations of the SES indicators with unknown diabetes were observed. However, the odds of having IGT was lower with higher occupational status in men (adjusted OR 0.7; 95% CI 0.5-0.9).
Undiagnosed type 2 diabetes was related to low SES defined by occupation or income in women only. In men, low occupational status was independently associated with higher IGT risk. Educational level was not related to glucose disorders in both sexes in the elderly population.
在老年人群中,研究了社会经济地位(SES)与未诊断糖尿病、糖耐量受损(IGT)以及2型糖尿病已知危险因素患病率之间的性别差异。
在德国奥格斯堡进行的2000年基于人群的KORA调查中,对1354名年龄在55 - 74岁的随机选择的受试者(697名男性,657名女性)进行口服葡萄糖耐量试验。通过逻辑回归,在控制年龄、腰围、血压、甘油三酯、身体活动、吸烟和饮酒量的情况下,估计按教育程度、职业和收入划分的未诊断糖尿病或IGT的优势比(OR)和95%置信区间(CI)。
在女性中,所有三个SES变量均与体重指数、腰围和低身体活动显著负相关(P < 0.05)。在男性中,这些关联较弱或不存在。以最低类别为参照,在多变量回归中控制危险因素后,职业地位与女性未诊断糖尿病显著相关(调整后的OR为0.5;95% CI为0.3 - 0.8)。女性中,收入较高时OR也降低(调整后的OR,糖尿病:0.7;95% CI为0.5 - 1.03)。在男性中,未观察到SES指标与未诊断糖尿病有显著关系。然而,男性职业地位较高时患IGT的几率较低(调整后的OR为0.7;95% CI为0.5 - 0.9)。
仅在女性中,未诊断的2型糖尿病与由职业或收入定义的低SES相关。在男性中,低职业地位与较高的IGT风险独立相关。在老年人群中,教育水平与两性的血糖紊乱均无关。