Chu Dominique, Lee Hoong-Chien, Lenaerts Tom
School of Computer Science, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Artif Life. 2005 Summer;11(3):317-38. doi: 10.1162/1064546054407176.
The DNA of some naturally competent species of bacteria contains a large number of evenly distributed copies of a short sequence. This highly overrepresented sequence is believed to be an uptake signal sequence (USS) that helps bacteria to take up DNA selectively from (dead) members of their own species. For some time it has been assumed that the USS evolved in order to enable bacteria to distinguish between conspecific and nonconspecific DNA fragments (the preference-first hypothesis). Recently, Redfield suggested that this hypothesis is not in fact realistic, as it would require biologically implausible group selection. In this article we present a model designed to demonstrate the emergence of similar USSs in a population of simulated evolving agents. We use this model to examine the conditions under which a USS will emerge in a preference-first scenario.
一些具有天然感受态的细菌物种的DNA含有大量短序列的均匀分布拷贝。这种高度富集的序列被认为是摄取信号序列（USS），它帮助细菌从自身物种的（死亡）成员中选择性地摄取DNA。一段时间以来，人们一直认为USS的进化是为了使细菌能够区分同种和非同种的DNA片段（偏好优先假说）。最近，雷德菲尔德认为这个假说实际上并不现实，因为它需要生物学上不太合理的群体选择。在本文中，我们提出了一个模型，旨在展示在一群模拟进化的主体中类似USS的出现。我们使用这个模型来研究在偏好优先的情况下USS出现的条件。
