嵌合抗原受体：针对一个问题儿童的三种新模型。
CAR: three new models for a problem child.
作者信息
Moore David D
机构信息
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
出版信息
Cell Metab. 2005 Jan;1(1):6-8. doi: 10.1016/j.cmet.2004.12.006.
PMID:16054039
Abstract
By comparison with its older and better-behaved cousins in the nuclear receptor superfamily, CAR (NR1I3) has always been an oddball. Three new crystal structures recently described in Molecular Cell reveal the molecular basis for some of its bad habits (Xu et al., 2004; Suino et al., 2004; Shan et al., 2004).
摘要
与核受体超家族中那些更为古老且行为规范的同类相比，组成型雄烷受体（CAR，NR1I3）一直是个异类。《分子细胞》杂志最近报道的三项新晶体结构揭示了其某些不良习性的分子基础（徐等人，2004年；苏伊诺等人，2004年；单等人，2004年）。
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