Mucilli Felice, Marolla Alessandro, Camplese Pierpaolo, Cipollone Giuseppe, Sacco Rocco
UO di Clinica Chirurgica, Scuola di Specializzazione in Chirurgia Toracica, Dipartimento di Scienze Chirurgiche, Università degli Studi G. D'Annunzio, Chieti.
Chir Ital. 2005 Jul-Aug;57(4):409-15.
The role of surgery in the treatment of diffuse pleural malignant mesothelioma is controversial. The procedures proposed to date are extrapleural pneumonectomy, pleurectomy, and thoracoscopy. External radiation or intraoperative implantation of radioisotopes, chemotherapy and intrapleural treatment with various different agents are also considered as adjuvant therapy. Patient selection, postoperative morbidity and mortality and survival rates are discussed. Our personal series of 72 diffuse pleural malignant mesotheliomas is described: 29 had a palliative operation while 43 underwent radical surgery consisting in 24 extrapleural pneumonectomies and 19 pleurectomies.
手术在弥漫性胸膜恶性间皮瘤治疗中的作用存在争议。迄今为止所提出的手术方式有胸膜外全肺切除术、胸膜切除术和胸腔镜检查。外照射或放射性同位素术中植入、化疗以及用各种不同药物进行胸膜腔内治疗也被视为辅助治疗。文中讨论了患者选择、术后发病率、死亡率及生存率。本文描述了我们个人所治疗的72例弥漫性胸膜恶性间皮瘤病例:29例行姑息性手术,43例行根治性手术,其中包括24例胸膜外全肺切除术和19例胸膜切除术。