颞叶切除术后的痴笑发作状态：发作期氟代脱氧葡萄糖正电子发射断层扫描结果及下丘脑错构瘤相关的双重病理问题
Status gelasticus after temporal lobectomy: ictal FDG-PET findings and the question of dual pathology involving hypothalamic hamartomas.
作者信息
Palmini Andre, Van Paesschen Wim, Dupont Patrick, Van Laere Koen, Van Driel Guido
机构信息
Neurology Service & Epilepsy Surgery Program, Hospital São Lucas da PUCRS, Porto Alegre, Brazil.
出版信息
Epilepsia. 2005 Aug;46(8):1313-6. doi: 10.1111/j.1528-1167.2005.52804.x.
PURPOSE
To present the first ictal fluorodeoxyglucose-positron emission tomography (FDG-PET) evidence of the hypothalamic origin of gelastic seizures in a patient with a hypothalamic hamartoma (HH) and to raise the issue of true dual pathology related to this entity.
METHODS
Ictal FDG-PET was acquired during an episode of status gelasticus with preserved consciousness, in a patient previously operated on for complex partial seizures (CPSs) due to a temporal lobe epileptogenic cyst.
RESULTS
Ictal hypermetabolism was localized to the region of the HH during the status gelasticus. CPSs had been completely eliminated after temporal lobe surgery.
CONCLUSIONS
Ictal FDG-PET independently confirmed that gelastic seizures in patients with HH do originate in the diencephalic lesion. An HH may coexist with another epileptogenic lesion, in a context of dual pathology.
目的
呈现首例下丘脑错构瘤（HH）患者笑性癫痫起源于下丘脑的发作期氟脱氧葡萄糖正电子发射断层扫描（FDG-PET）证据，并提出与此实体相关的真正双重病理问题。
方法
在一名因颞叶致痫囊肿曾接受复杂部分性癫痫（CPS）手术的患者，在意识清醒的笑性癫痫持续状态发作期间进行发作期FDG-PET检查。
结果
在笑性癫痫持续状态期间，发作期高代谢定位于HH区域。颞叶手术后CPS已完全消除。
结论
发作期FDG-PET独立证实HH患者的笑性癫痫确实起源于间脑病变。在双重病理情况下，HH可能与另一个致痫病变共存。
Zotero 插件