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[骨质疏松症及骨质疏松性骨折一级预防的循证最佳实践指南]

[Evidence-based, best-practice guidelines for primary prevention of osteoporosis and osteoporotic fractures].

作者信息

Tamaki Junko, Iki Masayuki

机构信息

Department of Public Health, Kinki University School of Medicine, Japan.

出版信息

Clin Calcium. 2005 Aug;15(8):1312-8.

Abstract

Community health interventions aimed at increasing peak bone mass and decreasing lifelong bone loss could substantially reduce the incidence of osteoporosis and osteoporotic fractures. Before now, no evidence-based practice guidelines for primary prevention of osteoporosis and osteoporotic fractures have been produced for public health center workers, primary care providers, and community health specialists. We constructed guidelines that present the effects of life-style factors, such as food and nutritional intake, in (1) increasing peak bone mass among young adults, (2) minimizing bone loss among menopausal and postmenopausal women, and (3) preventing fractures among the elderly. To do this, we systematically reviewed relevant evidence on the effects of physique, milk, dairy products, vitamin K, vitamin C, vitamin A, magnesium, and isoflavones. The guidelines provide optimum intake values and recommendations for young adults, women, and the elderly.

摘要

旨在增加峰值骨量并减少终生骨质流失的社区健康干预措施,可大幅降低骨质疏松症和骨质疏松性骨折的发病率。在此之前,尚未为公共卫生中心工作人员、初级保健提供者和社区健康专家制定基于证据的骨质疏松症和骨质疏松性骨折一级预防实践指南。我们制定了指南,阐述了食物和营养摄入等生活方式因素在以下方面的作用:(1)增加年轻人的峰值骨量;(2)尽量减少绝经和绝经后女性的骨质流失;(3)预防老年人骨折。为此,我们系统回顾了有关体格、牛奶、乳制品、维生素K、维生素C、维生素A、镁和异黄酮作用的相关证据。该指南提供了针对年轻人、女性和老年人的最佳摄入量值及建议。

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