Gabbe Belinda J, Cameron Peter A, Wolfe Rory, Simpson Pam, Smith Karen L, McNeil John J
Department of Epidemiology and Preventive Medicine, Monash University and Metropolitan Ambulance Service, Melbourne, Victoria, Australia.
ANZ J Surg. 2005 Aug;75(8):650-6. doi: 10.1111/j.1445-2197.2005.03484.x.
The present study explored a range of variables to identify predictors of mortality and morbidity and to develop prediction models based on these variables.
Tools for predicting mortality, hospital length of stay and a patient's destination post-hospital discharge were developed using logistic regression in one dataset (design) and evaluated for prediction performance in a separate dataset (validation). The performance of the mortality model was compared to the trauma and injury severity score (TRISS) and a severity characterization of trauma (ASCOT).
The profile of variables contributing to the final prediction models developed from the design dataset varied across the different outcomes of interest although age, injury severity score, development of complications and triage category were common predictors of all three outcomes. The performance of the new mortality prediction model was superior to both TRISS and ASCOT in the validation dataset. Overall, the new models did not meet the prespecified performance criteria.
The present study identified key predictors of mortality and morbidity (length of hospital stay and discharge destination). The newly developed mortality model out-performed published trauma scoring methods. However, further development and trial of the new prediction models is required before implementation as definitive audit and benchmarking tools could be recommended.
本研究探讨了一系列变量,以确定死亡率和发病率的预测因素,并基于这些变量开发预测模型。
在一个数据集中使用逻辑回归开发了预测死亡率、住院时间和患者出院后去向的工具(设计),并在另一个独立数据集中评估其预测性能(验证)。将死亡率模型的性能与创伤和损伤严重程度评分(TRISS)以及创伤严重程度特征(ASCOT)进行比较。
尽管年龄、损伤严重程度评分、并发症的发生和分诊类别是所有三个结局的常见预测因素,但从设计数据集中开发的最终预测模型所涉及的变量概况在不同的感兴趣结局中有所不同。在验证数据集中,新的死亡率预测模型的性能优于TRISS和ASCOT。总体而言,新模型未达到预先设定的性能标准。
本研究确定了死亡率和发病率的关键预测因素(住院时间和出院去向)。新开发的死亡率模型优于已发表的创伤评分方法。然而,在将新的预测模型作为确定性审计和基准工具推荐实施之前,需要对其进行进一步开发和试验。