Wilson Claire L, Miller Crispin J
Paterson Institute for Cancer Research, Manchester M20 4BX, UK.
Bioinformatics. 2005 Sep 15;21(18):3683-5. doi: 10.1093/bioinformatics/bti605. Epub 2005 Aug 2.
Quality Control is a fundamental aspect of successful microarray data analysis. Simpleaffy is a BioConductor package that provides access to a variety of QC metrics for assessing the quality of RNA samples and of the intermediate stages of sample preparation and hybridization. Simpleaffy also offers fast implementations of popular algorithms for generating expression summaries and detection calls.
Simpleaffy can be downloaded from http://www.bioconductor.org.
Additional information can be found on the supplementary website located at http://bioinformatics.picr.man.ac.uk.
质量控制是成功进行微阵列数据分析的一个基本方面。Simpleaffy是一个BioConductor软件包,它提供了各种质量控制指标,用于评估RNA样本以及样本制备和杂交中间阶段的质量。Simpleaffy还提供了用于生成表达汇总和检测调用的流行算法的快速实现。
可以从http://www.bioconductor.org下载Simpleaffy。