Chen Yang K
University of Colorado Hospital, Denver, Colorado, USA.
Curr Opin Gastroenterol. 2005 Sep;21(5):595-600. doi: 10.1097/01.mog.0000174224.82406.aa.
Endoscopic therapies for gastroesophageal reflux disease represent a minimally invasive alternative to medical or surgical treatment. These devices include suturing, radiofrequency energy, and bulking agent technologies. Research into the use of these technologies in gastroesophageal reflux disease continues to accelerate, and the last 2 years have witnessed significant developments that may affect current and future clinical practice.
Long-term data from nonrandomized clinical trials have become available in the last 2 years for many gastroesophageal reflux disease endotherapies, providing some insight into their durability. Furthermore, two multicenter and one single-center sham-controlled trials were published recently, allowing comparison between groups.
Although it is premature to propose the superiority of any individual approach, emerging data in this rapidly evolving field may inform current and future directions in the research and treatment of gastroesophageal reflux disease.
胃食管反流病的内镜治疗是药物或手术治疗之外的一种微创替代方法。这些设备包括缝合、射频能量和填充剂技术。对这些技术在胃食管反流病中的应用研究仍在加速，过去两年见证了可能影响当前和未来临床实践的重大进展。
在过去两年中，许多胃食管反流病内镜治疗的非随机临床试验的长期数据已经可得，这为其耐久性提供了一些见解。此外，最近发表了两项多中心和一项单中心假手术对照试验，从而能够在组间进行比较。
尽管现在提出任何一种方法的优越性都为时过早，但在这个快速发展的领域中出现的数据可能为胃食管反流病的研究和治疗的当前及未来方向提供参考。
