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[后颅窝成人脉络丛乳头状瘤:脑室外位置]

[Adult choroid plexus papilloma of the posterior fossa: extraventricular location].

作者信息

Mitsuyama Tetsuryu, Ide Mitsunobu, Hagiwara Shinji, Tanaka Noriko, Kawamura Hirotsune, Aiba Motohiko

机构信息

Department of Neurosurgery, Tokyo Women's Medical University Daini Hospital, Japan.

出版信息

No Shinkei Geka. 2005 Aug;33(8):825-9.

Abstract

Choroid plexus papillomas (CPPs) are rare neuroectodermal neoplasms accounting for 0.4% of all intracranial neoplasms in adults. Most of them are located in the posterior fossa in adults. Although CPPs commonly arise from the 4th ventricle, they occasionally extend to extraventricular space. Furthermore some occur primarily in the extraventricular region. It is difficult to diagnose CPP preoperatively when the main portion of the tumor is not located in the 4th ventricle. We present a case of a 54-year-old male manifesting slurred speech, nystagmus and cerebellar ataxia. Magnetic resonance imaging demonstrated an intracerebellar solid tumor with multilocular cysts, extending towards both the right lateral medullary region and the foramen of Luschka. Computed tomography scans showed patchy calcification at the periphery of the solid component. Angiographically, via the right posterior inferior cerebellar artery revealed the tumor was faintly opacified. Preoperative diagnosis included meningiomas, low-grade astrocytomas, ependymomas or CPPs, but none of them had neuroradiologically decisive findings. Tumor was subtotally resected through a right suboccipital craniectomy. A calcified solid portion adhering to the lower cranial nerves was left unresected. The pathological finding was CPP. CPP should be considered among calcified and enhanced masses in the lateral medullary to cerebellopontine angle space in adults, even if the main portion of the tumor is not located in the 4th ventricle.

摘要

脉络丛乳头状瘤(CPPs)是罕见的神经外胚层肿瘤,占成人所有颅内肿瘤的0.4%。在成人中,大多数脉络丛乳头状瘤位于后颅窝。虽然脉络丛乳头状瘤通常起源于第四脑室,但它们偶尔会延伸至脑室外间隙。此外,一些脉络丛乳头状瘤主要发生在脑室外区域。当肿瘤的主要部分不在第四脑室时,术前诊断脉络丛乳头状瘤很困难。我们报告一例54岁男性,表现为言语不清、眼球震颤和小脑共济失调。磁共振成像显示小脑内有一个伴有多房囊肿的实性肿瘤,向右侧延髓区域和Luschka孔延伸。计算机断层扫描显示实性成分周边有斑片状钙化。血管造影显示,通过右小脑后下动脉可见肿瘤有轻微造影剂充盈。术前诊断包括脑膜瘤、低级别星形细胞瘤、室管膜瘤或脉络丛乳头状瘤,但均无神经放射学的决定性表现。通过右枕下开颅术对肿瘤进行了次全切除。附着于低位颅神经的钙化实性部分未切除。病理检查结果为脉络丛乳头状瘤。即使肿瘤的主要部分不在第四脑室,成人延髓外侧至桥小脑角区域内有钙化且强化的肿块时,也应考虑脉络丛乳头状瘤。

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