巴比妥类药物与钙激活三磷酸腺苷酶
Barbiturates and calcium-activated adenosine triphosphatase.
作者信息
Willow M, Johnston G A
出版信息
Neurosci Lett. 1979 Oct;14(2-3):361-4. doi: 10.1016/0304-3940(79)96175-5.
PMID:161001
Abstract
Anaesthetic barbiturates potentiate and convulsant barbiturates inhibit the calcium-activated adenosine triphosphatase (Ca-ATPase) activity in rat brain synaptosomes. Such differential effects and consequent modification of transmitter release may be important in the contrasting actions of these classes of barbiturates in vivo.
摘要
麻醉性巴比妥类药物可增强，而惊厥性巴比妥类药物则抑制大鼠脑突触体中钙激活的三磷酸腺苷酶（Ca-ATPase）的活性。这类不同的效应以及随之而来的递质释放改变，可能在这些类别巴比妥类药物在体内的不同作用中具有重要意义。
Zotero 插件